婴幼儿维生素营养状况及影响因素分析.docVIP

婴幼儿维生素D营养状况及影响因素分析 ［ ］0的根据收集病历信息，探讨与婴幼儿维 生素D缺乏的相关因素。方法选取广州市天河区妇幼 保健院2014年10月?2016年4月收治的191例婴幼 儿患者，对所有患儿进行静脉采血，并使用酶（电化 学发光）免疫分析法对血清中维生素D水平进行检测。 应用线性回归方法探索影响维生素D测量值的因素， 应用Logistic回归分析方法探索与维生素D缺乏相关 的因素。结果在191例患者中，179例为维生素D缺 乏，12例患者为维生素D相对缺乏。维生素D水平 线性回归分析显示：维生素D水平与月龄（P ［关键词］婴幼儿；维生素D;营养状况；因素分 析 ［ ］R723.2 ［ ］A ［ ］ 2095-0616 （2017） 06-52-03 ［Abstract］ Objective To investigate the vitamin D level in infants and young children, and to analyze the influencing factors of Vitamin D. Methods 191 infants and young children cured in Tianhe District Maternal and Child Health of Guangzhou Hospital from October 2014 to April 2016 were recruited.Venous blood was collected from all children, and serum vitamin D levels were measured using enzyme immunoassay.The linear regression method was used to explore the factors influencing the measurement of vitamin D, and the factors related to vitamin D deficiency were explored by Logistic regression analysis. Results Among the 191 recruited patients, 179 patients were vitamin D deficiencies and 12 patients had a relative lack of vitamin D. Linear regression analysis of vitamin D levels showed that the value of vitamin D levels were linearly related to age (P=0) and PTH levels (P=0), but not to sex (P=0.665) .Logistic regression analysis showed that vitamin D deficiency was not associated with gender (P=0.836, OR=0.882), age (P=0.644, OR=812) and PTH (P=0.743，OR=0.789). Conclusion There is a linear relationship between the level of vitamin D and PTH, but deficiency of vitamin D is not related to age，sex and PTH. [Key words] Infants； Young children； Vitamin D； Linear regression analysis； Logistic regression analysis 维生素D是人体必需的脂溶性维生素，人体中也 代谢相关的维生素主要是维生素D2和维生素D3，统 称为前体维生素D，无生物学活性，需与维生素D结 合蛋白相结合，对调节机体钙磷代谢发挥重要的生物 学作用［1］。维生素D是类固醇的衍生物，同时具有激 素样作用，需要与受体结合发挥生理作用。维生素D 对于人体钙盐的代谢具有重要的意义，能够维持正常 的钙磷水平，并且能够对甲状旁腺的功能进行调节 ［2-3］，缺乏维生素D会造成钙盐代谢障碍，引起骨质 发育障碍，导致佝偻病的发生［4］,严重时还能够引起 神经系统的发育异常。维生素D能够影响肾素、血管 紧张素系统进而对心血管系统进行调节。近年来，逐 渐有研究报道自身免疫性疾病、儿童支气管哮喘、孕 妇妊娠期糖尿病及感染性疾病也可能与维生