纤溶酶联合马来酸桂哌齐特治疗急性脑梗死临床的的疗效观察.docVIP

纤溶酶联合马来酸桂哌齐特治疗急性脑梗死临床的的疗效观察 　　【摘要】 目的 观察纤溶酶联用马来酸桂哌齐特治疗脑梗死的临床疗效。方法 将84例急性脑梗死患者随机分为两组，治疗组42例，纤溶酶100U+0.9%氯化钠注射液100 ml，ivdrip,1次/d×14 d，同时给予马来酸桂哌齐特注射液240 mg+0.9%氯化钠注射液250 ml，ivdrip,1次/d×14，对照组42例，给予丹红注射液20 ml+0.9%氯化钠注射液250 ml，ivdrip,1次/d×14，分别观察两组临床疗效及实验室指标的变化。 　　结果 治疗组有效率为 90.48%，对照组为 59.52% 差异有显著意义(P0.01)。 治疗组实验室指标及纤维蛋白原等均降低明显优于对照组(P0.01)。两组均无明显不良反应。 　　结论 应用纤溶酶联合马来酸桂哌齐特治疗急性脑梗死有明显疗效。? 　　【关键词】 纤溶酶；马来酸桂哌齐特；急性脑梗死 　　?? 　　 　　The Clinical observation of Fibrinolytic enzyme cinepzide Maleate, treatment of patients with acute cerebral infarction 　　 　　LIANG Xiu?jun, SUN Jin?hua. 　　People?s Hospital of Dezhou City, Shandong,253008,China 　　? 　　 　　【Abstract】 Objective To 　　observe fibrinolytic enzyme the clinical curative effect of and Cinepzide Maceate treatment of cerebral infarction.Methods 84 cases of acute cerebral infarction were randomly divided into two groups: treatment group in 42 cases, fibrinolytic enzyme 100 U+0.9% physiological saline, 100 ml ivdrip qd×14 d, to give at the same time the Cinepzide Mceleate 240 mg,+0.9% physiological saline, 250 ml ivdrip qd ×14 d, and the control group, 42 patients were given Danhong injection 20 ml injection+0.9% physiological saline, 250 ml ivdrip qd ×14 d.Observed the clinical curative effect of two sets and laboratory indexes to change. 　　Results the treatment group was 90.48 %, efficient compared with 59.52 % differences were significant (P0.01). The treatment group laboratory index and fibrinogen etc were significantly lower than in control group (P0.01). Both groups had no obvious adverse reactions. 　　Conclusion Using fibrinolytic enzyme and cinepzide Maleate treatment of patients with acute cerebral infarction have apparent curative effect.? 　　【Key words】 　　Fibrinolytic enzyme; Cubeozide Maleate; Acute cerebral infarction 　　? 　　作者单位：253017山东省德州市人民医院 　　 　　急性脑梗死是临床常见的急重症之一，其致死率及致残率较高，严重威胁着人类的健康。降低患者的生存质量，给家庭和社会带来沉重的负担，至今尚无一普遍有效的治疗方法。2008年11月至2011年11月我们采用的纤溶酶注射液联用马来酸桂哌齐特注射液治疗急性脑梗死42例获得满意疗效，报告如下。? 　　1 资料与方