我院87例呼吸系统感染住院患儿抗菌药物使用剖析.docVIP

我院87例呼吸系统感染住院患儿抗菌药物使用剖析 　　【摘要】目的：对我院呼吸系统感染住院患儿抗菌药物使用情况进行调查，分析其合理性，以期为临床合理用药提供参考和警示。方法：采用回顾性方法，从2014年6月1日到2014年9月30日期间在我院呼吸内科接受治疗的435住院病例中，随机抽取87例呼吸系统感染病例，针对抗菌药物用药品种、给药途径、疗程及联合用药等方面进行调查，用Excel2003对各项数据汇总，分析抗菌药物使用情况。结果：87例住院患者抗菌药物使用率为100%，涉及8大类，15个品种，其中以三代头孢菌素使用最频繁。27例进行病原学检查，5例阳性根据检查结果3例选用特殊使用级抗菌药物。联合用药23例（二联），联合用药比率为26.44%，最常用的联用方式为第三代头孢菌素+大环内酯类。抗菌药物使用疗程最短为3天，最长达到17天，平均为6.3±1.20天。结论：我院呼吸内科住院患儿抗菌药物使用存在使用率和选用起点偏高、个别病例疗程长、更换抗菌药物频繁等不合理现象，需要进一步加强监 　　督管理。 　　【关键词】呼吸内科;住院患儿;抗菌药物;使用分析 　　Utilization Analysis Of Antibacterials In 87 Hospitalized Children Cases With Respiratory Infection In Our Hospital 　　Hu Gaosheng， Guo Danping， Liu Dongmei 　　（Xiamen Children Hospital， Fujian Xiamen 361006，China） 　　【Abstract】Objective： To investigate the usage of antibacterials in hospitalized children with 　　respiratory infection in our hospital and analysis its rationality， so as to provide reference and caution for clinical rational drug use. Methods： The study of antibacterials utilization， such as the varieties of antibacterials，administration route，course of treatment and combination of drugs，was performed on 87 cases retrospectively and randomly selected from 435 in-patients with respiratory infection treated in respiratory department of our hospital between June 1st 2014 and September 30th 2014 by summarizing the data collection using Excel2003.Results： The utilization rate of antibacterials in 87 in-patients cases was 100%， which was related to 8 categories of antibacterials， including 15 varieties， and third-generation cephalosporins was the most frequently used.5 cases showed positive among the 27 cases performed with pathogenic examination， and three of them were treated by using special grade antibacterials according to the examination results. For the combined usage of antibacterials，23 cases was treated with two drugs， getting a rate of 26.44%， and the most common combined mode was the combination of third-generation cephalosporins and macrolide antibiotics.The shortes