急性重症高脂血症性胰腺炎临床特征剖析.docVIP

急性重症高脂血症性胰腺炎临床特征剖析 　　摘要：目的探讨急性重症高脂血症性胰腺炎的相关临床特点。方法以2013年1月~12月崇州市人民医院和重庆医科大学附属第一医院肝胆外科在院的急性重症胰腺炎患者作为研究对象，根据患者的临床资料，分为高脂血症（HLAP）组和胆源性（ABP）组，比较两组患者在年龄、性别、住院天数、血脂水平变化的差异。结果两组患者比较，年龄、性别、住院天数比较均有统计学差异。HLAP组TG水平明显高于ABP组，差异有显著统计学意义，而TC、HDL、LDL水平在两组之间均无统计学意义。结论急性重症高脂血症性胰腺炎患者的年龄偏小，男性居多，住院时间较长，且血清TG水平升高是区别HLAP与ABP的最大血脂特征。 　　关键词：高脂血症；重症胰腺炎；急性胰腺炎 　　Clinical Characteristics Analysis of Hyperlipidemic Severe Acute Pancreatitis 　　YOU Hong-yong1,CHEN Zhi-min1,BAI yan1,DU Cheng-you2,CHEN Kai-quan1 　　(1.Chongzhou City Peoples Hospital ,Chongzhou 611230,Sichuan,China;2. The First Affiliated Hospital of Chongqing Medical University,Chongqing 400016,China) 　　Abstract：ObjectiveTo investigate the clinical features of severe acute pancreatitis associated with hyperlipidemia . MethodsAnalysis was conducted on patients, who were hospitalized in Peoples Hospital of Chongzhou and the First Affiliated Hospital of Chongqing Medical University between January 2013 and December 2013, the patients were divided into hyperlipidemia (HLAP) group and biliary (ABP) group based on the clinical data, the difference in the two groups were compared for age, sex, hospitalization, changes in lipid levels. Results Comparison of the two groups, there was significant difference on age, sex and days of hospitalization. The TG levels were significantly higher in HLAP group (t =14.40, P0.0001), and TC, HDL, LDL levels were not statistically significant between the two groups. ConclusionSevere acute pancreatitis in patients with hyperlipidemia were main occurred on younger males ,had longer hospital stay , and the maximum difference features between HLAP and ABP were the elevated levels of serum TG . 　　Key words：Hyperlipidemia ;Severe pancreatitis ; Acute pancreatitis 　　急性胰腺炎可发生于任何年龄，是临床上常见的急腹症，它是胰腺自身消化的一种化学性炎症。高脂血症性急性胰腺炎（HLAP）是由高脂血症引起的，约占整个急性胰腺炎患者的1.3%~3.8%。本文比较了HLAP患者与急性胆源性胰腺炎（ABP）患者的基本情况和血脂水平，以进一步明确HLAP的临床特点，从而提高对HLAP的诊治及预防水平。 　　1资料与方法 　　1.1一般资料以2013年1月~12月崇州市人民医院和重庆医科大学附属第一医院肝胆外科在院的急性重症胰腺炎患者作为研究对象，收集患