on nerve accelerated
Studyautogenousregenerationby
withFK506
temporaryimmunosuppression
Abstract
hand that
Clinicalonhuman shownerveofthe
study allotransplantation
2~3mm/day,after is
grew immunosuppressant.Thespeed
allograft using
the
fasterthanthatin ofseveredhandat samelevel
autologousreplantation
to the nerve
1 itis mechanismof
mm/day).Sonecessary injury,
(about study
and under state.
repairregenerationimmunosuppressive
Inthe examinednerve andfunctional
presentstudy,we regeneration
inrats
recoveryreceivingFK506(tacrolimus)1.0mg/kgperday,comparing
withuntreatedcontrol ofthe
animals.Morphometric
analysisregenerating
evaluated and
fiberwas bylight electron ofsoleus
microscopy.Weight
and of was
muscle musclemeasuredin
contractilitytricepsleg comparison
withthe contralateral function
unopermed leg.Sciatic index(SFl)and
Evoked offunction.
Somato—Sensory
Potentials(SSEP)evaluatedrecovery
0casesofclinicalvolunteer
weretre
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