短期免疫抑制促进自体神经快速再生的-研究.pdf

短期免疫抑制促进自体神经快速再生的-研究.pdf

on nerve accelerated Studyautogenousregenerationby withFK506 temporaryimmunosuppression Abstract hand that Clinicalonhuman shownerveofthe study allotransplantation 2~3mm/day,after is grew immunosuppressant.Thespeed allograft using the fasterthanthatin ofseveredhandat samelevel autologousreplantation to the nerve 1 itis mechanismof mm/day).Sonecessary injury, (about study and under state. repairregenerationimmunosuppressive Inthe examinednerve andfunctional presentstudy,we regeneration inrats recoveryreceivingFK506(tacrolimus)1.0mg/kgperday,comparing withuntreatedcontrol ofthe animals.Morphometric analysisregenerating evaluated and fiberwas bylight electron ofsoleus microscopy.Weight and of was muscle musclemeasuredin contractilitytricepsleg comparison withthe contralateral function unopermed leg.Sciatic index(SFl)and Evoked offunction. Somato—Sensory Potentials(SSEP)evaluatedrecovery 0casesofclinicalvolunteer weretre

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