老年重症心力衰竭73例临床疗效剖析.docVIP

老年重症心力衰竭73例临床疗效剖析 　　[摘要] 目的 探讨治疗老年重症心力衰竭的临床疗效，为临床治疗提供依据。方法 整群选取该院2014年9月―2015年2月收治的老年重症心力衰竭的患者146例，随机分为对照组和治疗组各73例，对照组采用强心苷及硝普纳进行治疗，治疗组在强心苷及硝普纳治疗的基础上加用美托洛尔以及厄贝沙坦氢氯噻嗪进行治疗，30天后两组进行疗效比较，观察两组治疗效果。结果 治疗组显效35例（（47.94%），有效33例 （45.21 %），无效5例（6.85%），总有效率93.15%。对照组显效26例（35.62%），有效34例（46.58%），无效13例（17.81%），总有效率82.19%。总有效率χ2检验，P=0.044，治疗组效果明显优于对照组，P0.05，差异有统计学意义。结论 在采用强心苷及硝普纳治疗的基础上加用美托洛尔以及厄贝沙坦氢氯噻嗪联合治疗老年重症心力衰竭的疗效，效果显著，患者临床症状明显改善，心功能明显改善，有效提高患者的生存质量，值得临床推广应用。 　　[关键词] 老年；重症心力衰竭；临床治疗效果 　　[中图分类号] R4 [文献标识码] A [文章编号] 1674-0742（2015）11（b）-0063-02 　　[Abstract] Objective To investigate the clinical efficacy in elderly patients with severe heart failure so as to provide a basis for clinical treatment. Methods 146 elderly patients with severe heart failure admitted in our hospital from September 2014 to February 2015 were selected and randomly divided into control group and treatment group， with 73 cases in each. Both groups were treated by cardiac glycoside and sodium nitroprusside， the treatment group were treated by metoprolol， irbesartan and hydrochlorothiazide additionally. The clinical efficacy of the two groups was observed and compared after 30 days of treatment. Results In the treatment group， the treatment effect was markedly effective in 35 cases（47.94%）， effective in 33 cases（45.21%）， ineffective in 5 cases（6.85%）， the total effective rate was 93.15%. In the control group， the treatment effect was markedly effective in 26 cases（35.62%）， effective in 34 cases（46.58%）， ineffective in 13 cases（17.81%）， the total effective rate was 82.19%. The result of chi-square test showed that the total effective of the treatment group was much better than that of the control group， with statistically significant difference， P=0.044， P0.05. Conclusion Metoprolol， irbesartan and hydrochlorothiazide combined with cardiac glycoside and sodium nitroprusside have significant effect on elderly patients with severe heart failure， which can effectively improve the clinical symptoms and heart func