成人房间隔缺损介入治疗和外科手术的对比研究-外科学专业论文.docx

目 录 中文摘要····························································································· （ 1 ） 英文摘要····························································································· （ 2 ） 论文题目····························································································· （ 4 ） 资料与方法 ························································································· （ 4 ） 结果··································································································· （ 6 ） 讨论··································································································· （11） 结论··································································································· （14） 参考文献····························································································· （14） 文献综述····························································································· （17） 参考文献····························································································· （27） 缩略语表····························································································· （31） 攻读学位期间发表文章情况 ···································································· （32） 个人简历····························································································· （33） 致谢··································································································· （34） 中 文 摘 要 目的 研究成人 ASD（房间隔缺损）介入治疗及外科手术的临床效果及术后心律失 常的影响因素。方法 回顾分析我院自 2008 年 10 月至 2013 年 10 月以来，于我院治疗 的 250 例继发孔型 ASD 患者临床资料，依据治疗方式将其分为介入组（n=108）与手术 组（n=142），介入组经导管介入治疗，手术组经心内直视修补术治疗，术后均随访 1 年， 分别于术后 1 月、3 月、6 月、12 月进行 ECG、TTE 等相应检查。观察对比两组手术成 功率，观察对比两组手术时间、住院时间、输血量、ASD 直径、存在残余分流的比例、 术后并发症的发生情况、手术费用，观察对比同组术前、术后各时点 RA（右房内径）、 RV（右室内径）、LA（左房内径）、LV（左室内径）各腔室容积的改变情况，观察对 比治疗前后两组房性心律失常的发生情况，并探讨术后房性心律失常的影响因素。结果 介入组 ASD 直径（19.59±6.91）mm，明显低于手术组（25.62±7.08）mm，具有统计学意 义（P＜0.05），介入组术后 1 例出现残余分流，手术成功率为 98.15%，手术组手术成功 率为 100.00%，两组相较，不具明显差异（P＞0.05），介入组手术时间、住院时间、输 血