灯盏花素对吸烟大鼠脑血管内皮细胞ICAM-1和ICAM-1+mRNA表达影响的实验分析.pdfVIP

fromvascular endothelialcellsin5differentcortical the fields，measure averagegrey scaleof their the scaleofvascularendothelial kytoplasm,calculate averagegrey ineachanimalcerebralcortex．Theresults kytoplasm were t-testor analyzedusing ANOVAand SPSS13．0．Avalue processedby P0．05wasconsidered statistically significant． Results ThereWas little ofICAM一1and very expression ICAM．1mRNAincerebral corticalvascularendothelial ratsin of Wasmost kytoplasm non-smokinggroup．Them ofICAM一1andICAM-1mRNAin expression cerebralcorticalvascularendothelial ofmtsin ofICAM-1andICAM．1mRNA kytoplasm smoking group．Theexpression Waslessin inhibitor smoking+PKC group． The ofvariance measuresof scaleatvarious analysis byrepeated kytoplasmgrey time ininfarct indicatesthat points group theearlierPKCinhibitoris more given,the effectofblocktheincreaseoflCAM-1andICAM一1mRNA expression． Conclusions PKCinhibitorCandecreasethe ofICAM．1andICAM．．1mRNAin expression cerebralcorticalvascularendothelialcellsof