Ⅱ类启动子调控CRISPR系统中sgRNA表达实现特异性的基因突变-生物学；发育生物学专业毕业论文.docxVIP

CONTENTSCoNTENTS CONTENTS CoNTENTS Abstract in Chinese ．．1 Abstract in English．．．． ．．．．．．．． ．．．．． ．．．．．．．．．．．．． ．．．．．．．． ． ．．．．．．．．．．．． ．．．． ．．．．． ．．．．．．．．． ．． ． ．．．．．III 1 Introduction ．1 1．1 CRISPR／Cas9 system ． ． ．． ． 1 1．1．1 Discovery ofCRISPR／Cas ．1 1．1．2 Structure ofCRISPR／Cas 1 1．1．3 Mechanism ofCRISPR／CaS 2 1．1．4 Classificafion ofCRISPR／Cas ．3 1．1．5 Progress ofCRISPR／Cas9 ．．4 1．1．6ApplicationofCRISPR／Cas9 ．． ．5 1．1．7 Induced regulation ofCRISPR／Cas9 system