丹参川芎嗪辅助治疗电弧烧伤的疗效分析-国际中医中药杂志.PDF

国际中医中药杂志2015年6月第37卷第6期 Int J Trad Chin Med, June 2015, Vol. 37, No.6 ²505 ² ²论著² 丹参川芎嗪辅助治疗电弧烧伤的疗效分析 张明 于燕 叶祥柏 【摘要】 目的 评价丹参川芎嗪辅助治疗电弧烧伤患者的临床疗效。方法 本研究为随机对照研 究。将符合纳入标准的50 例电弧烧伤患者按随机数字表法分为2 组各25 例，对照组视全身情况进行补 液、抗休克、抗感染及局部清创磨痂等治疗，治疗组在对照组基础上加用丹参川芎嗪静脉滴注，(10 ml/d ， 共7 d)。结果 7 d 时[(25.7 ±3.1)% 比(21.3 ±3.0)% ；t ＝5.122，P ＝0.000]和 14 d 时[(60.3 ±8.6)% 比 (53.8 ±10.8)% ；t ＝2.434 ，P ＝0.022]治疗组创面愈合率显著高于对照组；21 d 时2 组创面愈合率比较， 差异无统计学意义[(99.4 ±1.7)% 比(98.7 ±2.7)% ；t ＝1.163，P ＝0.265]。治疗组、对照组愈合时间分别 为(18.9±2.5)d、(20.3 ±2.2)d，2 组比较差异有统计学意义(t ＝-1.216，P ＝0.020)。结论 采用丹参川芎 嗪辅助治疗电弧烧伤可提高术后7、14 d 的创面愈合率、缩短愈合时间。 【关键词】 烧伤，电；中草药；丹参；川芎嗪 Salvia miltiorrhiza and ligustrazine as an adjuvant therapy in the patients with electric arc burns Zhang Ming, Yu Yan, Ye Xiangbo. Department of Burn and Plastic Surgery, Navy General Hospital, Beijing 100048, China Corresponding author: Ye Xiangbo, Email: yxb6407@163.com 【Abstract 】 Objective To evaluate the therapeutic effect of Salvia miltiorrhiza and ligustrazine as an adjuvant therapy in the patients with electric arc burns. Methods Fifty patients with electric arc burns were divided into 2 groups according to the random number table, with 25 in each group. The patients in the treatment group received intravenous infusion of 10 ml Salvia miltiorrhiza and ligustrazine injection for 7 days in addition to the conventional therapies, and those in the control group only treated with conventional therapies. Results The rates of wound healing in the treatment group were significantly improved at 7 days(25.7% ± 3.1% vs. 21.3% ± 3.0%; t=5.122, P=0.000) and 14 days (60.3% ± 8.6% vs. 53.8% ± 10.8%; t=2.434, P=0.022) than the control group. While at 21 days, there was no significant difference between the two groups (99.4% ± 1.7% vs. 98.7% ± 2.7%;