急性肾盂肾炎应用左氧氟沙星的临床干预效果分析.docxVIP

急性肾盂肾炎应用左氧氟沙星的临床干预效果分析 1?齐鲁工业大学校医院全科门诊，山东济南250353； 2. 济南市槐荫区吴家堡计划生育服务站计划生育科，山东济南 250118 ［摘要］目的观察急性肾盂肾炎应用左氧氟沙星的临床 干预效果。方法将我院2010年4月?2013年11月确诊并 收治的110例急性肾盂肾炎患者随机分为临床组和参照组各 55例。临床组应用左氧氟沙星静脉滴注进而口服治疗，参照 组应用氨节青霉素静脉滴注治疗进而用磺胺甲恶哇口服治 疗。比照两组症状体征消失时间、临床疗效及治疗时间。结 果两组用药完成后，症状体征逐渐改善，临床组其症状体 征消失速度均显著好于参照组，差异有统计学意义（P0. 05）o 但临床组其平均治疗时长显著低于参照组，差异有统计学意 义（P0.05）。结论急性肾盂肾炎应用左氧氟沙星疗效确切, 迅速缓解症状体征、疗程短、安全性好。 ［关键词］急性肾盂肾炎；左氧氟沙星；氟喳诺酮 ［中图分类号］R692. 7 ［文献标识码］B ［文章编号］ 2095-0616 （2014） 16-61-03 Analysis of clinical intervention effects of levofloxacin on acute pyelonephritis WANG Lianqinl GUO Yanhong2 Outpatient Department of General Practice , School Infirmary of Qilu Industrial University , Ji nan 250353 , China ； 2. Department of Family Planning, Huaiyin District Wujiapu Family Planning Service Stations of Ji， nan City, Ji， nan 250118, China [Abstract] Objective To investigate the clinical intervention effects of levofloxacin on acute pyelonephritis. Methods 110 patients with acute pyelonephritis who were treated in our hospital from April 2010 to November 2013 were randomly divided into the clinical group and the reference group, with 55 patients in each group? The clinical group received intravenous drip of levofloxacin and then oral administration ； The reference group received int ravenous drip of penbr itin and t hen oral administration of sulfamethoxazole? The symptom and sign disappearance time , clinical efficacy and treatment time of the two groups were compared? ResuIts After the end of medication, the symptoms and sings improved gra.dua.il y. The clinical group was significantly better than the reference group in both symptom and sign disappearance time , with statistically significant differences (P0.05)? But the clinical group had significantly shorter average treatment duration than the reference group (PO. 05). Conclusion In the treatment of acute pyelonephritis, the application of levofloxacin shows accurate efficacy, relieves symptoms and signs rapidly, and has short treatment