维生素D和腰椎病变.pptxVIP

维生素D和腰椎外文研究进展 Vitamin D deficiency in individuals with a spinal cord injury:a literature review Study design: Literature review of studies investigating vitamin D status in individuals with a spinal cord injury (SCI).Objectives: Prevalence of vitamin D deficiency seems to be high in the general population. Little is known regarding such a deficiency in individuals with a SCI. This review aimed to examine the literature that investigated vitamin D status in this population.Setting: Switzerland.Methods: A literature review was performed to investigate the prevalence of vitamin D deficiency in individuals with a SCI and to determine the factors leading to deficiency. Results: Sixteen studies which met all the inclusion criteria were identified. All of these studies assessed total serum 25-hydroxy vitamin D status in individuals with an acute or chronic SCI. Overall, the prevalence of vitamin D deficiency or insufficiency seems to behigh (range: 32–93%) in this population compared with that in able-bodied persons. The main factors are immobility, low physical activity and bedrest, and therefore not enough exposure to sunlight. In addition, age, skin pigmentation, lesion level, occurrence of pressure ulcers, body mass index, season and latitude appeared to be further determinants for vitamin D deficiency. In athletes, playingtheir sport indoors or outdoors may have an additional role in developing vitamin D deficiency. Conclusion: The available studies suggest that individuals with a SCI are at increased risk for vitamin D insufficiency/deficiency. Nutritional strategies and supplementation recommendations need to be developed to prevent these conditions in SCI. 文献综述：脊椎损伤患者（SCI）的维生素D状况。背景介绍：1、充足的维生素D对老年人、儿童和运动员很重要。维生素D缺乏可能关系到许多疾病，例如：佝偻病，骨质疏松，骨质软化，心血管疾病，高血压，多发性硬化症，帕金森和老年痴呆症，癌症。 2、缺乏维生素D也会对神经肌肉产生影响，可能导致老年人受伤和跌倒的风险升高。3、脊椎损伤的患者大部分会有骨质疏松，缺乏维生素D又会加重骨质疏松。 4、在医院和临床上，关于补充维生素D 的方案还并未达成共识。5、维生素D缺乏的原因包括：食物中缺乏、阳光暴露不足、衣服遮挡、防晒剂的使用、季节和纬度纳入条件：1、 SCI or spina bifida （脊柱损伤或脊柱裂） 2、huma