新生儿惊厥148例临床分析.docxVIP

新生儿惊厥148例临床分析劳庆禄(南方医科大学附属小榄人民医院儿科528415)【摘要】目的探讨新生儿惊厥病因、临床特点及急救方法，减少惊厥及后遗症的发牛。方法回顾性分析我院2005年01月?2011年12月共收治的148例惊厥新生儿的临床资料。结果痊愈121例，有症状出院的19例，死亡5例，自动出院3例，20例遗留有不同程度神经系统后遗症。围产期窒息是引起惊厥的首要原因，其次是感染性疾病、糖及电解质紊乱、各类先天性遗传代谢病。发作类型以微小性发作为多见，其次为阵挛性发作。治疗重点在于止痉，首选苯巴比妥，14.9%的患儿足量用药不能控制。结论围产期窒息是导致新生儿惊厥的主要病因；苯巴比妥仍是抗惊厥的首选药物，少数患儿须加用二线药物；发作形式以微小性发作最为多见；EEG背景波是判断预后的一个良好的指示。【关键词】婴儿新生儿惊厥病因治疗预后【中图分类号】R748【文献标识码】A【文章编号】2095-1752 (2012) 32-0125-02Neonatal Shock Clinical Analysis of 148 Cases of Break OffLAO Qing-luDepartment of Pedaitrics, Xiao Lan Hospital of Southern MedicalUniversity ,XiaoLan,Zhongshan5528415 China)[Abstract 】Objective In vestigate the cause of neon ata I convulsionsclinical characteristics and first-aid methods, reduce the incidence of seizures and the sequelae.Methods Retrospective analysis of our hospital from Janu-ary 2005 to December 2011 in the total of 148 cases of eclampsia admitted to the clinical data of newborn.Results 121 cases of full recovery, discharged from hospital with symptoms of 19 cases, the death of five cases, three cases of automatic discharge, there are 20 cases left over from the nervous system sequelae of varying degrees.Caused by perinatal asphyxia is the primary cause of febrile seizures, followed by infectious diseases, sugar and electrolyte disorders, various types of congenital genetic metabolic diseases. Type of attack made little as often, followed by clonic seizures. To stop focusi ng on the reatme nt of seizures, Phe no barbital prefered ,14.9% of children with a sufficient quantiy of medicines still con not con trol.Conclusi ons Peri natal asphyxia is a major cause of neon ata I con vulsions； Phenobarbital is still the first choice anticonvulsant drug, a small number of children with sec on d-li ne drugs should be added; The from of attack to the most minor seizures; EEG wave backgro und is a good prog nosis instructions.【Key words]infantneonatalfebrile eizures etiology treatmen?tprog nosis新生儿惊厥是中枢神经系统疾病或功能失常的一种临床表现，各种病因可致惊厥发作，常提示严垂的原发