胶原贴敷料护理治疗面部皮炎40例疗效观察.docxVIP

胶原贴敷料护理治疗面部皮炎40例疗效观察 栾玉敏 吴佳理(贵阳市第二人民医院皮肤科 贵州贵阳550081) 【中图分类号】R758.3【文献标识码】A【文章编号】1672-5085 ( 2012 ) 28-0160-02 【摘要】目的观察胶原贴敷料在治疗面部皮炎中的临床疗效。方法75例面部 皮炎患者随机分为治疗组和对照组。治疗组40例皮损处均给予胶原贴敷料敷贴, 同时口服盐酸西替利嗪片和复方甘草酸昔胶囊，外用木科自配制剂湿敷液；对照 组35例未给予胶原贴敷料敷贴，其余治疗同治疗组，2周为1疗程，治疗结束 后进行两组疗效对比。结果 治疗组和对照组总显效率分别为87.50%和62.85%, 两组差异有统计学意义(chi;2= 69.62, Plt;0.001)，治疗组疗效优于对照组。结 论胶原贴敷料治疗面部皮炎能显著提高疗效，使用安全，耐受性好，无明显不 良反应，值得临床推广。 【关键词】胶原面部皮炎疗效 [Abstract] Objective To evaluate the efficacy of collagen dressing in therapy of facial dermatitis.Method Seventy five patients with facial dermatitis were randomly assigned to treatment group or control group.The 40 cases in treatment group were treated with collagen posted dressing, received cetirizine hydrochloride tablet and compound glycyrrhizin, and were given hydropathic liquid (made by our center); except collagen dressing, the 35 cases in control group received equal treatments as the treatment group.Two weeks was one course of the treatment.Effect was evaluated after a course of the treatment.Results the effective rate of the treatment group and the control group was 87.50% and 62.85% respectively.The difference was statistically significant (chi;2= 69.62, Plt;0.001), indicating the efficacy of the treatment with collagen dressing.Conclusion Collagen dressing can improve the effectiveness in treatment of facial dermatitis, and is safe and comfortable, without obvious side effect.Collagen dressing should be popularized in clinical treatment of facial dermatitis. 【Key words] Collagen dressing; Facial dermatitis; Efficacy 面部皮炎是由诸多因素导致的皮肤炎症反应，常见诱因其多，治疗方法 多样，疗效不一。笔者从20□年10?2012年4月采用胶原贴敷料（商品名：创 福康，广州创尔生物技术有限公司生产）治疗面部皮炎40例，取得满意疗效，结 果报道如下。 1资料与方法 1.1诊断标准⑴[2]:⑴面部皮炎：定义为发生于面部的皮炎，排除其他 疾病如座疮、酒渣鼻、单纯疱疹、系统性红斑狼疮和单纯光敏感引起的面部受累。 ⑵接触性皮炎:按照教科书，接触性皮炎通过病史和临床表现诊断，包括变应性 接触性皮炎和刺激性接触性皮炎。⑶季节性面部皮炎：定义为面部皮炎病程超过 2年，为季节性发作，排除化妆品变应性接触性皮炎。（4）原因不明的面部皮炎： 为不能归于接触性皮炎和季节性面部皮炎的其他面部皮炎。 1.2 一般资料:75例患者均为我科2011年10?2012年4月诊治病例。 治疗组40例，其中男9例，女31例，年龄21?53岁，平均32.4岁，病程7 天?7年;对照组35例，其中男7例，女28例，年龄20?51岁，平均31