急性脑梗塞脑血流与脑功能的相关性研究-神经病学专业论文.docxVIP

山嚣r麓孚}大麟 山嚣r麓孚}大麟 羽陆拳位稍}文 急性脑梗塞脑血流与脑功雏的相关性研究 研究生 张晓雷 导烬 朵掇顺 教授 摘要 嚣的：对30铡脑梗塞(CI)急性期(72小时内)病人进行脑mL流 灌逢莲豫(SPECT)及毒枣经凝§§联系障碍与藏毫逡彩翌(B嚣AM)交位 之间关系进行探讨，为早期判断病情及预后，寻找谢效治疗方法提供理 论依据。方法：(1)对30例CI患者行发病瞄72小时内CT鼹像及脑皿 漉灌注显像，黯藏巍滚量逡行半定蘩分耩，并且进行72枣辩瘫藕藤弱 SPECT评分敷发病麟第4周的日常生活能力评分。(2)对30例cI患者 行脑电地形图(BEAM)定缀脑电参数比值(6+0)／(d十B)测定。 缭莱：(1)§藩梗塞瑶梗塞i炷遁域及遮隔部位的脑血滚灌注减少，其虻BF }匕值均小于0．9(2)脑电地形图亦显示定量麟电参数比值舞离，与rCBF 有明照的相关性，虽直线负相关(额叶F．0．741，颞叶户．0．762，顶叶 一O．779，梳时锄．724，P0．05)。(3)惫性翔SPECT与临床功能缺损评分 呈逡线正檩美(FO。83，P0，01)，与4髑时的爨霞生活缝力评分(BI)呈瓷线 负相关(F一0．79，P0．01)。结论：(1)脑血流灌注减少及其神经功能联系 障碍浮致脑功能减邋(2)扁部脑血流量与寇景脑电参数比值里负相关。 关键淫薤梗塞、弦灌液显像、簸电煞垒澎霭 山西匮抖大掌 山西匮抖大掌 习E士掌位·论文 Study on correlation between Cerebral Blood Flow and Brain Function in patients with acute cerebral infarction ABSTRACT Objective To discuss the relationship between the regional cerebral blood flow(rCBF)， the diaschisis and the change of(6+0)／(o+B)in acute cerebral infarction(C0，This may give us a better understanding of new forms of treatment．Methods 30 patients underwent CT within 24 hours and single-photon emission—computed temograplay(SPECT)within T2 hours after onset of CI,we also studied the change of (6}0)／(a+B)on brain electrical activity mapping(BEAM)．Semiquantitative rCBF were measured using SPECT．SPECT graded scale，neurological grading within 72h affter onset and Barthel Index(BF)of 4 weeks after onset WCDD evaluated．Results(1) The rCBF in infarct and its surrounding area decreased．The ration of rCBF was less than 0．9．(2)The detection of BEAM showed that the ration of(6+0)／(d+13)was improved．There was a significant linear correlation between the change of rCBF and the ration of(6+0)／(Q+13)(frontal lobe i-=-0．741，temporal lobe F-0．762．parietal lobe r=-0．779，occipital lobe r=一0．724．P0．05)．(3)Linear Correlation between SPECT Graded Scale