黄芪多糖对VC大鼠血中CO浓度及睾丸微细结构的影响-中医外科学专业毕业论文.docxVIP

成 成 都 中 医 药 大 学 硕 士 论 文 - - PAGE 7 - rest rats in the rest groups and got specimen with the same method like doing in the 4-week groups 8 weeks later. Results: There was statistic difference in the injury of inside diameter of contorted seminiferous tubules, altitude of seminiferous epithelium, spermatogenic cells in different stages and limiting membrane in every 2 groups (P﹤0.05) except the high-dosage-8-week group and sham-operation group(P﹥0.05). About the injury of the 3 indexs the rats in the APS groups and low-dosage groups were superior than control group and saline group(P﹤0.01). The absorbance of CO in spermatic vein blood was higher than before for the modle rats.About the absorbance of CO the rats in APS groups ,high-dosage groups ,8-week groups were inferior than that in control group and saline group,low dosage group and 4-week groups pespectively. There was statistic difference in the absorbance of CO in every 2 groups(P﹤0.01). Conclusion: There were protective effect for APS on testis damage caused by varicocele and related to the herb concentration and time. The spermatogenic dysfuction may correlated with the concentration of CO. The concentration of CO could be the susceptibility index for spermatogenic tissue injury earlier in clinic for VC patients. Astragalus polysaccharide can reduce the concentration of CO in blood of rats caused by VC. Keywords: Astragalus polysaccharids; Varicocele; CO; fine structure; tunicapropriatestis 中英文缩略词表 缩略词 APS English Astragalus Polysaccharides 中文 黄芪多糖 VC varicocele 精索静脉曲张 CO FS carbon monoxide fine structure 一氧化碳 微细结构 TAT HO tunicapropriatestis heme oxygenase 界膜 血红素氧合酶 ROS Reactive oxidative species 活性氧机制 成 成 都 中 医 药 大 学 硕 士 论 文 - - 65 - 附件四： 声 明 硕士学位论文：黄芪多糖对 VC 大鼠血中 CO 浓度及睾丸微 细结构的影响是本人在成都中医药大学攻读硕士学位期间，在导师 指导下完成的，该论文成果归成都中医药大学所有。有关学位论文成 果的开发、转让、论文发表等，均需征得导师和成都中医药大学同意。 硕士生签名： 导师签名： - - PAGE 10 - 前 言 精索静脉曲张(varicocele,VC)是指精索蔓状静脉丛，由于各种原 因引起回流不畅或因静脉瓣损坏引起血液倒流，导致局部静脉扩张、 迂曲和伸长的病理改变。VC是导致