OCM在血液透析中的应用.docVIP

OCM在血液透析中的应用 摘要： 目的：探讨分析血液透析中应用在线清除率(OCM)监 测尿素清除指数(KT/V)的应用价值。方法：选取2011年9 月至2013年8月我院血液净化中心收治的维持性血液透析 患者120例，作为研究对象。对全部血液透析患者每月1次 采用OCM在线监测KT/V值，同时采血测定该患者透析前后 的血浆尿素氮值，采用Daugirdas公式计算本次透析的KT/V 值，采集两种方法的监测数据，并进行分析。结果：OCM在 线监测不同干体重(彡50kg; 50kg)患者获得KT/V分别为 (1.50±0. 35)和(1.37±0.51)，采血测定不同干体重 (^50kg； 50kg)患者血浆尿素氮值经Daugirdas公式计 算 KT/V 值分别为(1.51±0. 13)，(1.42±0. 63)，二者比较 差异不明显，P0. 05,不具有统计学意义。结论：采用OCM 在线监测血液透析患者的KT/V，监测结果数据可靠、准确， 可实现实时监测，并且操作较为简单，具有良好的应用效果， 具有临床推广的价值。 关键词：在线清除率(OCM)；血液透析 Application of OCM in hemodialysis Abstract： Objective： Analysis on the application of online during hemodialysis clearance rate (OCM) monitoring urea clearance index ( KT/V ) value. Methods: 2011 September to 2013 August in our hospital blood purification center were selected in 120 patients on maintenance hemodialysis, as the object of study. Of all the patients with hemodialysis 1 times per month use OCM on-line monitoring KT/V value, at the same time, blood was taken for the determination of plasma urea nitrogen before and after the dialysis patients, using Daugirdas formula to calculate the dialysis KT/V, monitoring data acquisition of two methods ， and analysis. Result： OCM online monitoring of different dry weight (50kg； 50kg) in patients with KT/V were (1.50 ± 0. 35) and (1.37 ± 0.51)， were measured by different dry weight (50kg； 50kg) patients plasma urea nitrogen values by Daugirdas formula to calculate KT/V values were (1.51 ±0. 13)， (1.42 土 0. 63)，no obvious difference between the two, P 0. 05, not statistically significant. Conclusion : Use OCM on-line monitoring KT/V of hemodialysis patients, the monitoring data is reliable and accurate, and can realize the real-time monitoring, and the operation is simple, has good application effect, has clinical value. Key words： Online clearance rate (OCM)； Chronic nephritis； Hemodialysis 【中图分类号】 R552【文献标识码】B【文章编号】1002-3763 (2014) 08-0019-02 血液透析（HD）是临床上治疗急慢性肾功能衰竭的主要 治疗方式，由于肾功能障碍患者无法进行清除代谢废物、维 持正常的水-电解质平衡，因此需进行血液透析，将血液用 导管引流至透析机中，通过弥散、对