利用fMRI技术研究健康人针刺足三里穴的脑内效应神经外科专业论文.docxVIP

Every Every subject completed the following tasks: (1) acupuncture at sham acupoint Study on fMRI Brain Map in Healthy Adult Undergoing Needling at Zusanli (ST36) M.Candidate：LinWuRong Mentor：Prof. Zheng Shao-qin Abstract Objective To observe the characteristic of the fMRI brain map in healthy adult undergoing needling at the acupuncture point Zu San Li （ST36）, for exploring the essence of the meridian and the mechanism of treating diseases through acupuncture point Zu San Li （ST36）,which can provide the objective and the central action theoretical evidence。 Materials and Method The twelve healthy volunteers were all students from the medical college, six males and six females, all right-handed, aged from 22 to 27 years (average 25.2 ±1.44 years). None of the subjects had nervous system disease or a psychiatric history. They did not take any sedatives or receive acupuncture treatment within three days and two weeks before the trial, respectively. （ （3）The brain functional regions activated by acupuncture at the right Zu San (lateral area of the left leg 20mm from Zu San Li ); (2) acupuncture at the left Zu San Li (ST36)；(3) acupuncture at the right Zu San Li (ST36). The data from the brain functional imaging were analyzed with the internationally used analysis of functional neuroimages (AFNI) software (edition: 2008_02_01_1144). After the reconstruction of the images, the data from the three tasks were aligned based on the third TR through time alignment and manual rectification followed by spatial smoothing (FWHM=4 mm). The F values (6, 1121) obtained in the deconvolution analysis from the standardization of the signal change rate was verified using a t-test. The fMRI imaging was recollected under the Talairach coordinate with a size of 3 mm X 3 mm X 3 mm. The activated area in the functional imaging was obtained after averaging the results of 12 subjects, and the regions with a signal greater than three pixels were defined as the activated regions (P0.005). Result