流动人口对结核病传播的影响-数学;应用数学专业论文.docxVIP

摘要摘要 摘要 摘要 结核病感染了大约世界上三分之一的人口，平均每年全世界有大约300多 万人因结核病去世．流动人群是结核病全球传播的主要原因之一．本文采用了 建立数学模型的方法来研究流动人群对结核病传播的影响． 全文分为三章：第一章介绍了结核病的流行概况和一些关于研究结核病的 数学模型．第二章在传统的结核病模型的基础上，把总人口分为两类：流动人群 和本地人群，建立并分析了流动人群对结核病传播影响的基本数学模型，利用 Lasalle不变集原理、Lapunov函数及Hurwith判据证明了无病平衡点的全局 渐近稳定性．同时利用第二加性复合矩阵原理证明了惟一地方病平衡点的全 局渐近稳定性．第三章在基本数学模型基础上，考虑流动人群系统中潜伏类及 染病类均有常数输入的数学模型，此时，不论系统的基本再生数取什么值，疾病 都不会消失，并在本地人口中形成地方病．利用第二加性复合矩阵原理可以证 明地方病平衡点是全局渐近稳定性． 以上研究分析表明流动人群会对结核病的传播产生很大的影响：要从人群 中彻底消除结核病，必须解决流动人群的结核病问题． 关键词 结核病； 流动人群； 平衡点； 第二加性复合矩阵． Abstract Abstract Abstract Tuberculosis infects roughly one—third of the world’S population，killing more than three million people every today．The immigrant population was responsible for transmission of tuberculosis in worldwide．The aim of this work iS to construct mathe· matical models to study the impact of immigrant population on tuberculosis transmis- sion． The full text iS divided into three chapter：the first chapter introduced the preva- lence of tuberculosis and some mathematical models about the study of tubemul0一 sis transmission．the second chapter established the basic mathematical model about the impact of immigrant population on tuberculosis transmission and analyze asymp。 totic behavior of these models．The total population is divided into the immigrant subpopulation and local subpopulation．By Lyapunov function and LhSalle invari。 ant set theorem，Hurwitz criterion，the stability disease-flee equilibrium is proved．The global asymptotically stability of the endemic equilibrium is also proved by using the compound marx theory．The third chapter presents the extended model which incorporated the recruitment of the latent and infectious in immigrants to the basic model．Then，the threshold condition doesn’t exist and a unique equilibrium exists．This indicates that the disease does not disappear and becomes endemic． Through mathematical studied we find immigrants have a considerable influ- ence on the transmission dynamics behavior of tuberculosis．To control of dis