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Abstract
diseaseandits
ofakindof incidence
diseaseiscolnmon
Allergic
the of
treatmentfor the
antihistaminecaneffective disease,alleviatesuffering
allergic
tobe a one thenew
fexofenadine quitepromisingamong
patients.The appears
allthecriteriaforanidealH1
antihistaminesit fuifillsalmost
since
littleside
hasobviouscurativeeffect.Ithas
clinicalvalidation:fexofenadine
long.term
market
effectandnosedativefunction,andvery prospects.
good
and researchbasedontheauthor
This inthedomestic report puts
topic foreign
forwardtwo shouldtake reactionbeforeoxidationwith
innovation.First,wecyclization
and the ofother
sidechainonbenzene
the tO the ring preventgeneration
protect
potassium
we the after the and of
openring oxidation,improvingpurityyieldproduct.
products.Then
before reactiontoreducethe
shouidtakereductionreaction
Second,we N—alkylation
andthecostofrea
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