老年高血压患者血压晨峰与内皮功能、心脏重构及颈动脉内—中膜厚度关系的研究-内科学(心血管病学)专业论文.docxVIP

塑坚查堂!!堕旦堡主垦兰童些兰垡丝奎The 塑坚查堂!!堕旦堡主垦兰童些兰垡丝奎 The study of the relationship between morning blood pressure surge of patients with elderly hypertension and endothelial function，myocardial remodeling and carotid imtima media thickness Department of internal medicine(Cardiology) Medical college ofZhejiang University Master’S candidate lUO li jU Supervisor fu guo sheng ABSTRACT Objectives：To study the relationship between morning blood pressure surge @毋Ps)ofpatients with elderly hypertension and endothelial function,myocardial remodeling and carotid imlLma media thickness by measu血g ambulatory blood pressure,vasoactive substances that synthesis and secrete from endothelial cells， myocardial remodeling and imtima media thickness and plaques ofcarotid． Methods：sixty patients with elderly hypertension were separated into two groups by the degree of MBPS．Them,three patients whose MBPS is no less than 50mmHg are included in the first group and twenty seven patients whose MBPS is less than 50mmHg are included in the second group．NO and ETol in$踟dnl 8a-e measul戡l on all patients by nitric∞id revrt end／me analysis and ray inllnllne analysis and the patients all are examined by M-mode echocardiography and carotid ullrasonography． Results：h the丘rst group．the content ofNO in serum was lower；the content ofET-1 in samm and the ratio of left ventricular hypertrophy were higher than that in the second group．The di益erence was statistically distinct 00．05)．There is 110 statistic difference bctwegn the ratio of the imtima media thickness and plaques of carotid in two groups 0o．05)． 2 浙江大学2006届硕士医学专业学位论文Conclusion：The 浙江大学2006届硕士医学专业学位论文 Conclusion：The degree of MBPS in patients with elderly hypertension is closely relaWxi with the insult degree of endothelial function,myocardial remodeling and is not distinctly related with ratio ofimtima media thickness and plaques ofcarodd． Key words：hypertension Morning Blood Pressure Surge(MnPS) Endothelial function myocardial remodeling carotid imtim