苓桂术甘汤加味对脾虚痰湿型2型糖尿病胰岛素抵抗的临床分析-中医内科学专业论文.docxVIP

英文摘要 英文摘要 苓桂术甘汤加味对脾虚痰湿型 苓桂术甘汤加味对脾虚痰湿型 2 型糖尿病胰岛素抵抗的临床研究 5 5 PAGE PAGE 6 Clinical Study on Insulin Resistance of Spleen Phlegm Stagnation Syndrome of 2-Type Diabetes Mellitus (2-DM) with modifying Linggui zhugan Decoction Chen Xiaohui(Internal Medicine of Traditional Chinese Medicine) Directed by Shi Hefeng Abstract Objective：To explore the clinical effect of insulin resistance of spleen phlegum stagnation syndrome of 2-type diabetes mellitus with Linggui zhugan decoction. Methods：82 cases of spleen phlegum stagnation syndrome of 2-DM were divided int two groups at random: control group and treatment group, each group of 41 examples. The former was treated with dimethyldiguanide and the latter was treated with dimethyldiguanide modifying Linggui zhugan decoction. Both groups were treated for 3 months, during which clinical symptom scores of before after treatment, fasting plasma glucose (FPG), 2-hour postprandial blood glucose (2hPG), glycosylated hemoglobin (HbAlc), fasting plasma insulin (FINS), insulin sensitivity index (IAI), Homeostasis model assessment (HOMA-IR), lipids and other indicators were observed. Results：After the treatment, TCM clinical syndrome of treatment group was obviously better than that of control group(P 0.05). TCM syndrome scoring weree significantly improved compared with that in control group (P 0.01). Indicators of both groups, such as FPG、2hPG、HbAIC、IAI differed significantly before and after the treatment(P0.05). Compared with pretreatment, the level of HOMA-IR decreased obviously, the difference being significant as compared with control group (P0.05). Compared with pretreatment, the level of CHOL, TG and LDL of treatment group decreased while the level of HDL increased. The differences both were of statistical significance (P0.05). The level of CHOL,TG and HDL of treatment group after treatment is significant from that of control group(P0.05). The overall effiency of treatment group has significant difference with that of contr