翼状胬肉两种不同切除术患者泪液功能的临床分析.docVIP

翼状警肉两种不同切除术患者泪液功能的临床分析 李大鹏（通讯 ） 戴静 （江苏省东海县人民医院眼科 222300） 【 】目的 探讨两种不同手术方式治疗翼状窗肉对泪液功能的影响及影响因 素。方法 选取翼状警肉患者60例（60只眼）随机分成两组：A组30个病人（30 只眼）翼状窗肉联合结膜瓣移植术；B组30个病人（30只眼）翼状窗肉切除联 合带自体角膜缘干细胞结膜瓣移植术。术前，术后4周，术后12周行泪膜破裂 时间（BUT）、泪液分泌试验（Schirmer I）.角膜荧光素染色（CSF），评价翼状窗 肉及翼状窗肉切除术后泪膜功能变化对患者牛活质量的影响。结果两组病人术 后4周BUT缩短，角膜荧光素染色增多，差异有统计学意义（plt;0.05）,而术后 Schirmer I与术前相比无统计学意义,两组术后12周BUT, Schirmer I, CFS与术前 相比无统计学意义，翼状窗肉切除联合带自体角膜缘干细胞结膜瓣移植术组术后 早期泪膜稳定性优于翼状歸肉联合结膜瓣移植术，差异具有统计学意义 （plt;0.05）.结论翼状警肉切除术早期对泪膜功能有影响。翼状警肉切除联合带 自体角膜缘干细胞结膜瓣移植术早期对泪膜的影响小于翼状窗肉联合结膜瓣移 植术。 【关键词】翼状窗肉 泪膜 翼状窗肉切除 角膜缘干细胞 【中图分类号】R777.33 【文献标识码】A 【文章编号】2095-1752 （2013） 27-0072-02 Clinical analysis of two different surgical methods on tear function in patients with pterygium LI Da-peng,Daijing,Departmeng Of Ophthalmology,the Peoplersquo;Hospital of Donghai CountyQonghai County 222300,China Corresponding author:li dapeng, Email：163.com 【Abstract】Objective To explore the two different surgical methods on tear function in patients with ptergium and its possible factors.Method Sixty cases of pterygium patients (60 eyes) were randomly divided into two groups: A group of 30 patients (30 eyes) underwent pterygium excision combined with conjunctival flap,B group of 30 patients (30 eyes) underwent wing-shaped pterygium excision combined with autologous limbalstem cell transplantation . Respectively before and 4 weeks ,12weeks after surgery the tear film break-up time (BUT), Schirmer I test, conjunctiva fluoresce in staining (CFS)，To evaluate the effects of tear function changes in pteryqium and on quality of patients life after pterygium excision 。 Results Of two groups of patients 4weeks post-operation BUT shortened, CFS in creased, and the differe nces were sign 讦 ican t (plt;0.05), while the differe nee between postoperative and preoperative Schirmer I was insign讦icant, As for 12 weeks post-operation BUT Schirmer I, CFS postoperative and preoperative differenee of two groups was not sign讦icant. Tear film stability of group B was bett