呼吸支持治疗COPD合并痰堵窒息的临床观察和分析.docxVIP

呼吸支持治疗COPD合并痰堵窒息的临床观察和分析 曾建明曾春芳冯银合 (德阳市人民医院呼吸内科618000) 【摘 要】目的：探讨呼吸支持(有创机械通气)治疗COPD合并痰堵窒息的 临床疗效。方法：回顾2007年11月-2014年9月我科呼吸支持(有创机械通气) 治疗58例COPD合并痰堵窒息患者，按是否给予呼吸支持(有创机械通气)分 为治疗组和非治疗组，分析比较两组的治愈率及死亡率，并对结果采用统计学分 析。结果：按GOS标准；呼吸支持治疗联合抗牛素、糖皮质激素、氨茶碱、沙 丁胺醇等常规治疗COPD合并痰堵窒息的治疗组治愈率为94.7%,明显高于非治 疗组治愈率10%(P0.05)；同时，治疗组死亡率为5.26%,亦明显低于非治疗组 死亡率90%(P0.05)o结论：及时有效的呼吸支持(有创机械通气)治疗联合抗 牛素、氨茶碱、沙丁胺醇等治疗COPD合并痰堵窒息，可有效地控制病情，提高 治愈率，降低死亡率。 【关键词】COPD痰堵窒息；呼吸支持；抗生素；糖皮质激素；氨茶碱；沙 丁胺醇 【中图分类号1R563.8 【文献标识码]B 【文章编号11003-5028(2015) 6-0549-02 [Abstract JObjective: to investigate the respiratory support (invasive mechanical ventilation) for COPD patients with phlegm blocking choke the clinical therapeutic effect. Methods: retrospective analysis the cases were treated by respiratory support treatment (invasive mechanical ventilation) in our department in November 2007 to September 2014. According to whether used the respiratory support treatment (invasive mechanical ventilation) ,58 cases of COPD with phlegm blocking choke were divided into treatment group or non treatment group, compared two groups of the cure rate and mortality. The results were statistically analyzed. Results: according to GOS standard; Treatment group who was treated by respiratory support was used of antibiotics,glucocorticoids, aminophylline and albuterol treatment, the cure rate of the treatment group (94.7%) was sign讦icantly higher than non treatment group (10%) (P lt; 0.05); the mortality of treatment group(5.26%) was obviously less than the non treatment group(90% )(P lt; 0.05). Conclusion: with antibiotics, aminophylline and albuterol treatment, the timely and effective respiratory support treatment (in vasive mecha nical ven tilati on) of COPD with phlegm blocking choke can effectively control the condition, improve the cure rate and reduce mortality. 【key words] COPD sputum plugging choke respiratory support antibiotics glucocorticoid amin ophylli ne albuterol 慢性阻塞性肺疾病(Chronic Obstructive Pulmonary Disease,以下简称 COPD) 是常见的呼吸系统疾病，严重危