密歇根筛查量表对糖尿病神经病变的诊断价值.docx

密歇根筛查量表对糖尿病神经病变的诊断价值 208 Tianjin Med JMar 72013Vol 41 No 3 doil03969jissn0253-9896201303005 密歇根筛杳量表对糖尿病神经病变的诊断价值 1 1 △ 1112 张春风 谢 云 Priyadarshini Yonzon 尹爱莉徐津咏崔壮 摘要目的探讨密歇根神经病变筛查量表MNSI在诊断糖尿病周 围神经病变DPN中的价值方法糖 尿病患者267例分别进行MNSI筛查和神经电牛理检查依MNSI体检 评分将患者分为A组024分112例B组25 44分88例及C组245分67例比较各组间的性别年龄及病程等一 般资料情况和神经电牛理检查结果的差异 对MNSI问卷中可能影响DPN的问题进行逐步Logistic回归分析将 MNSI问卷评分和体检评分与上述相关指标进行 相关性分析结果1A组患者年龄糖尿病病程低于BC组C组患者无波 形比例1642高于其余2组 P 005 2 A组患者的胫后神经运动神经波幅以及双下肢感觉运动神经传 导速度均高于BC组其DP确诊率 P 005 3MNSI问卷屮问题1211及14是 DPN的影响因素4 MNSI问卷评分与患者年 5089低于BC组 龄糖尿病病程呈正相关与胫后神经运动神经波幅双下肢感觉神经传导 速度呈负相关MNSI体检评分与患者年 感觉神经运动神经传导速度呈负相关 P 005结论以MNSI问卷评分4分体检评分2分为截点能较好诊 断出神经电生理异常且DPN的检出率明 显提高 关键词糖尿病神经病变电生理学人体质量指数神经传导诊断 鉴别密歇根神经病变筛查量表MNST ThcEvaluationofthcMichiganMcuropathyScrccninglnstrumcntinthcDiagnosis of DiabeticPeripheralNeuropathy ZHANG Chunfeng XIE Yun Priyadarshini Yonzon YIN A订i XU Jinyong CUI Zhuang 1 Department of Neurology Metabolic Disease Hospital of Tianjin Medical University The Key Laboratory of Hormone and Development of the Ministry of Hca1th Tianjin 300070 China 2 Department of Health StatisticsSchool of Public Health rr^ ? ? ? Tianjin Medical Uni versity [Abstract] Objective To investigate the value of the Michigan Neuropathy Serecning Instrument MNSI in the diagnosis of diabetic peripheral neuropathy DPN Methods A total of 267 patients with diabetes mellitus underwent the measurements of MNSI and neural electrophysiological test All of the participants were divided into three groups based on MNSI score 112 patients in group A score 0-24 88 in group B score 25-44 and 67 in group C score 245 The differences of gender age history of diabetes and neural electrophysiological test results were compared between three groups The stepwise logistic regression was used to analyze the effeet of MNSI questionnaire for the DPN The relationship between the MNSI questionnaire exam score and the index mentioned above was analyzed Results 1 The patients in group A were much younger and had a shorter history of d