传染病及真菌病 Infectious Diseases.ppt

Bacillary dysentery Bacillary dysentery ① Acute bacillary dysentery Clinic appearance Toxaemia—fever, peripheral blood leukocutosis. Inflammatory— abdominal cramping . irritation diarrhea with mucus, blood and pus in the stool. tenesmus. Complication: hemorrhage. perforation(less commonly). dehydration. electrolytic disturbance(in serious cases). Fate: healing (most cases). in some cases, protracted and pass into a chronic condition. ② Chronic bacillary dysentery Course of disease has been exceeded more than 2 months. Such chronic cases are characterized by repeated injury and repair, ulceration and healing, and can lead to new and old lesions coexist, chronic ulcer formation, polypoid mucosal irregularity with fibrous scarring and subsequent stenosis of the bowel. Clinic appearance: Abdominal pain, chronic diarrhea intestinal obstruction. ③ Toxic bacillary dysentery The most common in children. Often from organism of lower virulence. the onset of disease is sudden. Intestinal lesion is child, showing catarrh enteritis or follicular enteritis. There are severe general toxic symptoms (high fever, convulsion). After onset some hours, toxic shock and coma or brain edema and respiratory failure appear rapidly. Gonorrhea Gonorrhea is supprurative inflammation caused by gonococci and is one of the most common sexually transmitted disease, which has a high prevalence and very strong infectiousness. 1. Etiology and pathogenesis Pathogen —Neisseria gonorrhoeae(gonococci), gram-negative Diplococcus The organism is a facultative intracellular pathogen that binds to and invades epithelial cells through the pili in the envelope of gonococcus and secreted IgA proteo-lystic enzyme. The polysaccharides of capsular contribute to virulence