胃癌前病变的机理与治疗探讨.PDFVIP

2015年09月第35卷第5期 现摇 代摇 中摇 医摇 药 Sep.2015摇 Vol.35 摇 No.5 ModernTraditional Chinese Medicine ·7摇摇摇5 · 理 论 探 讨 * 胃癌前病变的机理与治疗探讨 杜晓泉摇 摇 唐尚友摇 摇 袁敏慧摇 摇 刘争辉 (陕西中医药大学附属医院脾胃病二科,陕西 咸阳 712000) 摘摇 要:胃癌前病变是虚实夹杂的病理状态,本虚以脾胃气阴两虚为主,标实则有络瘀、气滞、湿阻、毒瘀交 阻等。 由实致虚是其主要病机转化规律。 其中胃络瘀阻存在于整个病程。 气阴两虚,瘀阻胃络是胃癌前病变主 要病机,益气养阴活血法可以干预胃癌基因异常表达。 萎胃安煎剂能够逆转胃癌前病变的病理变化,改善胃 粘膜。 关键词:胃癌前病变;机理;治疗;探讨 中图分类号:R273摇 摇 文献标识码:A摇 摇 文章编号:1672-0571(2015)05-0075-03 DOI:10.13424/ j.cnki.mtcm.2015.05.033 On Mechanism and Treatment of Gastric Precancerous Lesions Du Xiaoquan,Tang Shangyou,Yuan Minhui,Liu Zhenghui (The Second Department of Spleen and Stomach Diseases,Affiliated Hospital of Shaanxi University of Chinese Medicine,Xianyang712000,China) Abstract摇 The pathological manifestation of gastric precancerous lesions was mainly mixture of deficiency and ex鄄 cess,namely viscera deficiency and excess in pathological factors. The viscera deficiency manifested in deficiency of spleen qi andstomachyin,whilepathologicalfactorsmainlywerebloodstasis,qistagnation,dampnessaccumulationand mixture of toxin aswell as phlegm. The pathogenesis conditions mostly transformed from excess to deficiency and blood stasis stagnated in gastriccollateralsinthewholedurationof disease. QiandYindeficiency aswellasphlegmobstructing gastric collaterals are major pathogenesisfor gastricprecancerouslesions. Themethodof replenishingqi,activatingblood and nourishing yin can interfere with the abnormal expression of cancer genes. Weiwei爷an Decocotion can prevent the pathological changes of gastric cancer and promote the condition of gastric mucosa. Keywords摇 gastric precanc