生殖生物学理论与相关技术-Implantation-讲稿2015.pptVIP

Trophoblast: L-selectin---Epithelia: MAd-CAM-1  Invading trophoblast Oxygen tension plays an important role in cytotrophoblast invasion The early stages: hypoxic environment migrate along the lumina of spiral arterioles, replacing the maternal endothelial Cytotrophoblasts are also found in the smooth muscle walls of these vessels. As a result, the diameter of the arterioles expands Spiral artery remodeling and preeclampsia Defect of extravillous trophoblast invasion  in myometrial spiral artery occurs in preeclampsia Cause