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Lipid-Metabolizing CYPs
in the Regulation and
.
y
l Dysregulation of Metabolism
n
o
e
s
u
g l
r a
o. n David Bishop-Bailey, Scott Thomson, Ara Askari,
s o
w s
r
e e
i p Ashton Faulkner, and Caroline Wheeler-Jones
v
e r
r o
l F
a
u . Comparative Biomedical Sciences, Royal Veterinary College, University of London,
n 5 London NW1 0TU, United Kingdom; email: dbishopbailey@rvc.ac.uk
n 1
a /
. 5
w 1
/
w 0
1
w
n
m o
o )
r C
f
d M
e U
d
a P Annu. Rev. Nutr. 2014. 34:261–79
o ( Keywords
l e
n g
w e First published online as a Review in Advance on
l
o l eicosanoids, polyunsaturated fatty acids, epoxygenase, CYP
D o April 24, 2014
. C
9 l
7 a Abstract
2 c The Annual Review of Nutrition is online at
i
1- d
e
6 The cytochrome P450s (CYPs) represent a highly divergent class of en-
2 M
:
4 n This article’s doi:
3. o zymes involved in the oxidation of organic compounds. A subgroup of CYPs
i
4 n 10.1146/annurev-nutr-071813-105747
1 U metabolize ω3-arachidonic and linoleic a
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