二氧化钛纳米材料的环境健康和生态毒理效应.docVIP

收稿日期:2007-11-03录用日期:2007-12-25 基金项目:国家自然科学基金“十五”重大项目(No科技部973资助项目(No.2006CB705603作者简介:王江雪(1978—,女,博士后;*通讯作者(Corresponding author ,E -mail:chenchy@nanoctr.cn 2008年第3卷 第2期,105-113 生态毒理学报 Asian Journal of Ecotoxicology Vol.3,2008No.2,105-113 二氧化钛纳米材料的环境健康和生态毒理效应 王江雪 1,2 ,李炜1,刘颖1,劳芳1,陈春英 1,* ,樊瑜波 2 1.国家纳米科学中心-中国科学院高能物理研究所纳米生物效应与安全性联合实验室,北京100080 2.北京航空航天大学生物工程系,北京100083 摘要:伴随着纳米科技的迅猛发展,各式各样的纳米材料被开发和生产出来,逐步进入到周围环境及生命体中,纳米材料的生物安全性和生态毒理学问题已引起了社会各界的普遍关注.纳米二氧化钛(TiO 2因具有良好的光催化特性、耐化学腐蚀性和热稳定性,而被广泛应用于涂料、废水处理、杀菌、化妆品、食品添加剂和生物医用陶瓷材料等与日常生活紧密相关的领域,因此,其将不可避免地进入环境和生态系统中引起相应的生物学效应(毒理学.论文从流行病学调查和实验研究两方面出发,综述了纳米TiO 2对生物体 (皮肤、肺、肝、肾和脑、细胞(细胞膜、细胞生长和凋亡和生态系统的影响,探讨了其毒性产生的可能机制.希望今后进一步加强对纳米TiO 2的环境健康和生态毒性研究,以建立纳米TiO 2的环境健康安全暴露评价体系,促进纳米技术的健康、安全和可持续发展.关键词:纳米材料;纳米二氧化钛;环境健康;生态毒理;活性氧 文章编号:1673-5897(20082-105-09 中图分类号:TB383,X171.5,X18 文献标识码:A Environmental Health and Ecotoxicological Effect of Titanium Dioxide Nanomaterials WANG Jiang -xue 1,2,LI Wei 1,LIU Ying 1,LAO Fang 1,CHEN Chun -ying 1,*,FAN Yu -bo 2 1.Laboratory for Bio -Environmental Effects of Nanomaterials and Nanosafety ,National Center for NanoScience and Technology - Institute of High Energy Physics ,Chinese Academy of Sciences ,Beijing 1000802.Bioengineering Department ,Beihang University ,Beijing 100083Received 3November 2007 accepted 25December 2007 Abstract :With the rapid development of nanotechnology ,many kinds of nanomatertials are manufactured and used in each field.They tend to enter the environment and life system.The problem of bio -environmental effects of nanomaterials and nanosafety has raised increasing concerns among many scientists and governments.Nanoscale titanium dioxide (TiO 2,a noncombustible and odorless white powder ,was widely used in the fields of paints ,waste water treatment ,sterilization ,cosmetics ,food additive ,and bio -medical ceramic materials ,etc.,because of its inherent advantages of the photocatalysis ,anticorrosion and high stability.Therefore ,it is unavoidable for nanoscale TiO 2to enter