GIST胃肠间质瘤治疗新进展讲课.pptVIP

* 这导致了许多的不同的分级系统，各个研究的分级指标互不相同 通常，分裂象1-5/10HPF的常伴有较高的转移潜能。必须注意的是，尽管高的分裂率通常提示恶性间质瘤，低的分裂率并不总是确保良性的病变。 要准确的量化有丝分裂率需要对肿瘤的各个部分细胞进行足够的取样。 * 有报道：11外显子突变者格列卫有效率78.5%，9外显子突变的45％，未检测到突变的仅9％ * The most easily applicable and recognised pathological criteria for prediction of recurrence risk are tumour size and mitotic rate, and over the last decade prognostic scales combining these two criteria have been evaluated * GIST harbouring either four of the five minor criteria, or one major criterion, are considered to have high malignant potential, while others are considered of low malignant potential With