瞬时弹性成像技术预测酒精性肝病合并食管胃静脉曲张破裂出血的临床研究.pdf

目 录 摘要 ······························································ ···························· 1 Abstract ······················································ ································ 3 前言 ······························································ ···························· 6 对象与方法 ······························································ ··················· 8 结果 ····························································· ··························· 14 讨论 ····························································· ··························· 18 结论 ······························································ ··························· 22 参考文献 ······························································ ····················· 23 综述 ······························································ ··························· 26 参考文献 ······························································ ····················· 38 中英文缩略词对照表 ······························································ ······ 45 攻读学位期间发表文章情况 ···························································· 46 致谢 ······························································ ··························· 47 个人简历 ······························································ ····················· 48 瞬时弹性成像技术预测酒精性肝病合并食管胃静脉曲张破裂出血的 临床研究 摘 要 背景 近年来，酒精性肝病（Alcoholic Liver Disease ，ALD ）的发病率及死亡率在全球 范围内逐渐上升。晚期 ALD 患者以合并食管胃静脉曲张破裂出血最为常见，并且再 出血风险极高，患者死亡率高、预后差。因此，早期检测患者肝脏病变程度、预防食 管胃静脉曲张破裂出血，对于降低病死率、减轻家庭负担有重要意义。 目的 探讨瞬时弹性成像技术（FibroScan ）检测ALD 患者肝硬度（Liver Stiffness Measure ，LSM ）值预测食管胃静脉曲张破裂出血的诊断价值。 方法 1.研究对象 连续纳入2018年4月至2019年4月就诊于郑州大学附属洛阳中心 医院