8鉴定致病基因Theory 生物信息学PPT技术文档.pptxVIP

基于高通量DNA测序数据的致病突变分析;;Learning objectives;Tonight, Im launching a new Precision Medicine Initiative to bring us closer to curing diseases like cancer and diabetes — and to give all of us access to the personalized information we need to keep ourselves and our families healthier — Barack Obama, State of the Union Address, January 20, 2015;Genetics: potential benefits;Types of genetic diseases;Nature?461, 747-753 (8 October 2009) |?doi:10.1038/nature08494 ;Single-gene diseases;Single-gene disorders;Molecular Mechanism;Sanger sequencing (双脱氧链终止法);Frederick Sanger;The Wellcome Trust Genome Campus