19Immune Repertoires-董俊超-20190618 生物信息学PPT技术文档.pptxVIP

Immune RepertoiresJunchao DongDepartment of Immunology, ZSSOMSun Yat-sen UniversityJune.18, 2019OutlinesWhat are immune repertoires? B cell receptor T cell receptorHow to detect immune repertoire? DNA level mRNA level protein levelHow to make good use of immune repertoire information? Basic research Clinical relevance？One gene, one proteinCentral dogma of molecular biologyAn enormous antibody repertoire is required to deal with huge amounts of pathogens to a living being Antibody repertoire is…the collection of antibody specificities available to an individualcontinuously shaped by exposure to