枸杞多糖联合白芍总苷治疗复发性阿弗他溃疡的疗效评定.docVIP

枸杞多糖联合白芍总昔治疗复发性阿弗他溃疡的疗效评定 枸杞多糖联合白芍总甘 治疗复发性阿弗他溃疡的疗效评定 王嬪姣1,李莉1,徐武清2,漆明1 【摘要】目的:评价枸杞多糖联合白芍总昔在治疗复发性阿弗他溃疡 (Recurrent Aphthous Ulcer,RAU)中的长期临床疗效及不良反应。方法：将 160例RAU患者随机分为两组,治疗组80例采用宁夏枸杞提取物枸杞多糖 联合白芍总昔治疗，对照组80例只采用白芍总昔治疗，两组疗程均为6 个月。根据屮华口腔医学会粘膜病专业委员会的“RAU疗效评价试行标准” 进行疗效评价。结果：枸杞多糖联合白芍总昔组治疗RAU患者总体冇效率 显著优于白芍总昔组，且不良反应较轻；两组RAU患者在治疗期内的总间 歇期均延长，溃疡总数目均减少，其对间歇期的影响，存在显著性差异(p 0.01)；对溃疡数目的影响，未见明显差异(pgt;0.05)o结论：枸杞多 糖联合白芍总昔治疗RAU长期疗效显著，不良反应轻微。 【关键词】枸杞多糖；白芍总昔；复发性阿弗他溃疡 【中国图书分类法分类号】 【文献标志码】A The clinical evaluation of Total Glucosides of Paeony and Lyeium Barbaom Polysaccharide in the treatment of Recurrent Aphthous Ulcer WANG Jingjiaol,U Lil,XU Wu Qing2, QI Mingl* (1. Stomatology hospital of ningxia medical university general hospital;2.Ningxia medical university institute of traditional Chinese medicinel,yinchuan 750004,) 【Abstract] Objective: To evaluate the Iong-term clinical efficacy and adverse reactions of the joint of LBP and TGR which in the treatment of recurrent aphthous ulcers (RAU). Methods: A total of 160 RAU patients were randomly基金项目：宁夏科技攻关计划项目(编号：201125) 作者单位：1.宁夏医科大学总医院口腔医院2?宁夏医科大学中医学院, 宁夏银川750004通讯作者：漆明，宁夏医科大学总医院口腔医院,E-mail: qiming61@si divided into two groups? The treatment group of 80 patients were treated with TGP and LBP extracting from Ningxia lyeium barbaom,and another 80 patients in the control group were treated with TGP only.The course for two groups was 6 months.Then evaluate the efficacy according to the RAU Evaluation trial standardsnof Chinese Stomatological Association Professional Committee of mucosal disease.Results: The efficiency of LBP combined with TGP group was significantly better than the TGP group, with less adverse reactions. Total intermittent period of two RAU thanthe TGP group, with less adverse reacti ons. Total intermitt ent period of two RAU patie nts groups were extended,and there was a significant differenee of its intermittent period (plt;0.01).There was no sign讦icant difference of the changes on the number of ulcers (pgt;0.05). Conclusion: