医学交流课件：ITP.pptVIP

ITP Diagnosis and treatment ITP: An autoimmune disorder characterized by persistent thrombocytopenia due to autoantibody binding to platelet antigen(s) causing their premature destruction by the reticuloendothelial system, and in particular the spleen Primary: no underlying cause Secondary: immune mediated but associated with an underlying disorder Chronic: lasted for more than 12 months Refractory: failed to respond to (or relapsed after) splenectomy and is severe (ie, associated with bleeding or bleeding risk that requires therapy) Primary（Adult） ITP Incidence：220/100 000/year