抗体、基因重排及B细胞发育.pptVIP

Antibody Molecules, Their Genes and B Cell Development ;获得性免疫系统的 “五项基本原则”;Three Topics Diversity Specificity Memory;7-1;a1;Diversity - Different Classes and Subclasses; 0 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 ;7-2 Basic Structure of Ab Molecules 抗体分子的基本结构;IgG分子由两条H链和两条L链共价结合而成。轻链包括VL和CL两个结构域，重链含有1个VH和3个CH 结构域。VH和VL共同组成抗原结合部位。Ig分子中线对称，具有两个相同的抗原结合部位。;???蛋白酶;Rodney Porter 1917-1985 Nobel Prize in 1972; 0 10 20 30 40 50 60 70 80 90 100