神经外科手术病人丙泊酚靶控输注复合舒芬太尼和芬太尼麻醉的效果比较临床医学.docVIP

神经外科手术病人丙泊酚靶控输注复合舒芬太尼和芬太尼麻醉的效果比较临床医学 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：神经外科手术病人丙泊酚靶控输注复合舒芬太尼和芬太尼麻醉的效果比较临床医学 2 1资料与方法 4 11一般资料 4 12麻醉方法 4 14统计学方法 5 22两组基础MAP和HR比较 6 文2：等效剂量的舒芬太尼和芬太尼应用于开颅手术麻醉的效果分析 7 1 资料与方法 7 （1）肝、肾、心、肺功能正常的患者。 8 （2）患者以及家属在手术前均与我院签署了《知情同意书》 8 （1）存在大出血以及过度肥胖的患者。 8 （2）存在精神疾病、沟通障碍以及意识不清醒的患者。 8 （3）存在严重内分泌疾病、血液疾病以及免疫系统疾病的患者。 8 （4）患者以及家属不同意进行此次研究的。 8 2 结果 9 3 讨论 10 参考文摘引言： 11 原创性声明（模板） 12 文章致谢（模板） 12 正文 神经外科手术病人丙泊酚靶控输注复合舒芬太尼和芬太尼麻醉的效果比较临床医学 文1：神经外科手术病人丙泊酚靶控输注复合舒芬太尼和芬太尼麻醉的效果比较临床医学 Abstract： ObjectiveTo evaluate the effects of sufentanil and fentanyl in combination with target-controlled infusion of propofol on patients undergoing neurosurgical adult patients of ASA grade I-II undergoing elective neurosurgical operation were randomly divided into two groups, . sufentanil group (Group S, n=20) and fentanyl group (Group F, n=20). Anesthesia was induced with midazolam, propofol and sufentanil (Group S) or fentanyl (Group F). After tracheal intubation, the patients in Group S received continuous intravenous infusion of sufentanil at a speed of ~ μg·kg-1·min-1 while the patients in Group F received a bolus of fentanyl when it was needed. Anesthesia was maintained by a targetcontrolled infusion of propofol with a initial target concentration of 2 μg/ml, which was increased progressively until satisfactory anesthesia was achieved. Sufentanil infusion was stopped after skin closure. The anesthetic efficacy of the two groups was evaluated based on hemodynamics(MAP and HR)at eight time points throughout the operation. After operation, time to spontaneous respiration recovery, eye opening and extubation were recorded. The OAA score was evaluated at 5 minutes after extubation. ResultsThe patients in Group F experienced significantly higher MAP after tracheal intubation and headpi iertion (P). The patients in Group S experienced significantly lower HR during tumor resection and skin closure (P). Time to