急性一氧化碳中毒后迟发性脑病46例临床分析.docVIP

急性一氧化碳中毒后迟发性脑病46例临床分析 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：急性一氧化碳中毒后迟发性脑病46例临床分析 1 1 临床资料 3 2 讨论 5 文2：急性一氧化碳中毒后迟发性脑病38例临床分析 6 1 资料与方法 6 2 讨论 8 参考文摘引言： 9 原创性声明（模板） 10 文章致谢（模板） 11 正文 急性一氧化碳中毒后迟发性脑病46例临床分析 文1：急性一氧化碳中毒后迟发性脑病46例临床分析 Clinical Analysis on 46 Patients with Delayed Encephalopathy after Acute Carbon Monoxide Poisoning Liu Chao, Wang Boyu ( Department of Internal Medicine, PLA 163rd Hospital, Changsha 410003, China) Abstract： Objective To sum up the clinical characteristics of delayed encephalopathy after acute carbon monoxide poisoning (DEACMP)Methods Data, such as manifestation, imaging, electroencephalogram (EEG), electrocardiogram (ECG), therapy and prognosis, were retrospectively analyzed on the 46 patients with DEACMP admitted to the hospital from Jan. 2003 to Jan. 2006Results All the patients suffered from cociousness disorde whose main manifestation was of the change in cociousness. The disorde sustained for ± hou and their pseudo healing duration was ± days. of the patients, 36 suffered from the disorder of extrapyramidal system and some suffered from that of pyramidal system. The abnormal rates of ECG, EEG, computerized tomography (CT) and magnetic resonance imaging (MRI) were % (20/46), % (32/32), % (32/46) and % (23/25), respectively. At last, there were 32 patients who healed up, 13 who improved, and one who died. Conclusion The main manifestation of DEACMP coists of cociousness disorde and functional disorde of extrapyramidal and pyramidal system. The patients disability rate will be high as soon as they occur. Key words： carbon monoxide poisoning; delayed encephalopathy 急性一氧化碳中毒（Acute carbon monoxide poisoning，ACOP）后迟发性脑病（delayed encephalopathy after acute carbon monoxide poisoning，DEACMP）是当今临床医生十分关注的热点问题。DEACMP是指急性一氧化碳中毒患者经抢救恢复，在急性期的意识障碍消失后经2~60 d 的“假愈期”又出现的一系列神经精神障碍，主要表现为意识障碍和锥体外系、锥体系功能障碍。DEACMP的发病机制迄今不明，至今尚无单一特效的救治方法。早期发现并给予合理氧疗，积极改善脑内微循环和神经细胞代谢水平，可望使病人的损伤降到最低限度，并可缩短病程，使多数病人逐渐康复，但治愈率不尽如人意。现将我院2003年1月—2006年1月住院治