99mTctetrofosmin显像在老年人甲状腺冷结节性质判定中的价值临床医学.docVIP

99mTctetrofosmin显像在老年人甲状腺冷结节性质判定中的价值临床医学 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：99mTctetrofosmin显像在老年人甲状腺冷结节性质判定中的价值临床医学 1 1 资料与方法 3 99mTcTF显像 3 99mTcTF图像分析 4 2 结 果 5 3 讨 论 5 文2：18FFDG显像在乳腺癌新辅助化疗疗效评价中的应用临床医学 6 1 材料与方法 8 18FFDG PET检查 8 2 结果 9 3 讨论 9 参考文摘引言： 11 原创性声明（模板） 12 文章致谢（模板） 13 正文 99mTctetrofosmin显像在老年人甲状腺冷结节性质判定中的价值临床医学 文1：99mTctetrofosmin显像在老年人甲状腺冷结节性质判定中的价值临床医学 【Abstract】 Objective To identify the diagnosis value of 99mTctetrofosmin imaging in thyroid “cold nodule” by comparing the diagnostic results of 99mTctetrofosmin imaging and neck Color Doppler Ultrasonography (CDU). Methods 60 patients with thyroid “cold nodule” determined by 99mTcO-4 imaging were chosen. Regarded pathological result as the standard and compared diagnostic value of 99mTctetrofosmin imaging and neck CDU in analyzing 96 thyroid “cold nodules”，62 thyroid “cold nodules” with diameter greater than 1 cm respectively. Results There were 52 cases of benign，44 cases of malignancy in 96 thyroid “cold nodules”. The accurate of neck CDU and 99mTcTF were % and % respectively，there was no significant difference（P＞）.There were 34 cases of benign, 28 cases of malignancy in 62 cases of thyroid “cold nodule” with diameter＞ 1cm. The accurate of neck CDU was %, there was no significant difference（P＞）comparing that in thyroid “cold nodule”. The accurate of 99mTcTF was %, higher than that in thyroid “cold nodule”（P＜）and that of neck CDU（P＜）. Conclusio 99mTcTF imaging is more seitive in large diameter thyroid “cold nodule” 【Key words】Thyroid；“Cold nodule”；Radionuclide imaging；Tetrofosmin 甲状腺癌在内分泌系统恶性肿瘤中排第一位，约占全身所有恶性肿瘤的1%～%，近年来有增高的趋势〔1，2〕。约有近95%的甲状腺癌表现为“冷结节”，而“冷结节”中有%～%为癌组织，因此术前明确“冷结节”的性质有重要意义〔3〕。99m锝1,2双〔双(2 乙氧乙基)膦基〕乙烷（99mTctetrofosmin，99mTcTF）,是临床常用的一种心肌显像剂，同时99mTcTF还被认为是一种有前途的亲肿瘤显像剂，已开始研究其在乳腺、肺等肿瘤组织诊断中的作用〔4～6〕，但目前为止国内未见其在甲状腺癌诊断方面的研究。本研究以病 理学 检查为标准，对颈部彩色多普勒超声（color doppler ultrasonography，CDU）检查和99mTcTF显像在甲状腺“冷结节”性质判定中的结果进行对比分析，以明确99mTcTF显像在