可必特与普米克令舒治疗哮喘性支气管炎的临床疗效分析.docxVIP

可必特与普米克令舒治疗哮喘性支气管炎的临床疗效分析 　　【摘要】目的研究吸入用复方异丙托溴铵溶液（商品名：可必特）与吸入用布地奈德混悬液（商品名：普米克令舒）治疗哮喘性支气管炎的临床效果。方法72例哮喘性支气管炎患者，采用抽签法分为观察组和对照组，各36例。对照组采用普米克令舒进行治疗，观察组在对照组基础上联合可必特进行治疗。对比两组患者症状体征消退时间、血气指标、住院时间与治疗效果。结果观察组气喘消退时间、哮鸣音消退时间、咳嗽消退时间、肺啰音消退时间及住院时间均短于对照组，差异有统计学意义（p0.05）。治疗后，两组动脉血氧分压与血氧饱和度均高于治疗前，动脉血二氧化碳分压低于治疗前，且观察组动脉血氧分压与血氧饱和度均高于对照组，动脉血二氧化碳分压低于对照组，差异均有统计学意义（p0.05）。观察组总有效效率97.22%高于对照组的83.33%，差异有统计学意义（p0.05）。结论哮喘性支气管炎患者采用可必特联合普米克令舒治疗能明显改善临床症状，且治疗效果显著。 　　【关键词】吸入用复方异丙托溴铵溶液;吸入用布地奈德混悬液;哮喘性支气管炎;血气指标 　　【abstract】objectivetostudytheclinicaleffectofcompoundipratropiumbromidesolutionforinhalation（tradename：combivent）andbudesonidesuspensionforinhalation（tradename：pulmicort）inthetreatmentofasthmaticbronchitis.methodsatotalof72asthmaticbronchitispatientsweredividedintoobservationgroupandcontrolgroupbylotterymethod，with36casesineachgroup.thecontrolgroupwastreatedbypulmicort，andtheobservationgroupwastreatedbycombiventonthebasisofthecontrolgroup.thedisappearancetimeofsymptomsandsigns，bloodgasindex，hospitalizationtimeandtherapeuticeffectwascomparedbetweenthetwogroups.resultsthedisappearancetimeofasthma，wheeze，cough，raleandhospitalizationtimeintheobservationgroupwasshorterthanthoseinthecontrolgroup，andtheirdifferencewasstatisticallysignificant（p0.05）.aftertreatment，thearterialoxygenpartialpressureandoxygensaturationinthetwogroupswashigherthanthosebeforetreatment，andarterialcarbondioxidepartialpressurewaslowerthanthatbeforetreatment.thearterialoxygenpartialpressureandoxygensaturationintheobservationgroupwashigherthanthoseinthecontorlgroup，andarterialcarbondioxidepartialpressurewaslowerthanthatinthecontrolgroup.theirdifferencewasstatisticallysignificant（p0.05）.thetotaleffectiverate97.22%intheobservationgroupwashigherthan83.33%inthecontrolgroup，andthedifferencewasstatisticallysignificant（p0.05）.conclusioncombiventandpulmicortshowsremarkableeffectinthetreatmentofpatientswithasthmaticbronchitis，anditcansignificantlyimprovetheirclinicalsymptoms. 　　【keywords】compoundipratropiumbromidesolutio