医学免疫学课件:IgE-FcεR Signaling in Immune Response.pptxVIP

医学免疫学课件:IgE-FcεR Signaling in Immune Response.pptx

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IgE-FcεR Signaling in Immune Response ;Manikandan, J., et al., Deciphering the structure and function of FcepsilonRI/mast cell axis in the regulation of allergy and anaphylaxis: a functional genomics paradigm. Cell Mol Life Sci, 2012. 69(12): p. 1917-29.; IgE-FcεR interaction 1.1 FcεRI 1.2 IgE-FcεRI interaction 1.3 CD23 (FcεRII) 1.4 IgE-CD23 interaction 2. FcεR mediated signaling 2.1 FcεRI mediated signaling 2.2 CD23 mediated signaling 3. Advance in FcεR mediated signaling;IgE-FcεR interaction ;αβγ2;IgE-FcεRI interaction ;CD23 (FcεRII) ;IgE-CD23 interaction;IgE-FcεR interaction ;FcεR mediated signaling ;FcεR mediated signaling ;Wu, L.C., Immunoglobulin E receptor signaling and asthma. J Biol Chem, 2011. 286(38): p. 32891-7.;FcεR mediated signaling ;Wu, L.C., Immunoglobulin E receptor signaling and asthma. J Biol Chem, 2011. 286(38): p. 32891-7.;Wu, L.C., Immunoglobulin E receptor signaling and asthma. J Biol Chem, 2011. 286(38): p. 32891-7.;Wu, L.C., Immunoglobulin E receptor signaling and asthma. J Biol Chem, 2011. 286(38): p. 32891-7.;Wu, L.C., Immunoglobulin E receptor signaling and asthma. J Biol Chem, 2011. 286(38): p. 32891-7.;Sibilano, R., B. Frossi and C.E. Pucillo, Mast cell activation: a complex interplay of positive and negative signaling pathways. Eur J Immunol, 2014. 44(9): p. 2558-66.;FcεR mediated signaling ;Wu, L.C., Immunoglobulin E receptor signaling and asthma. J Biol Chem, 2011. 286(38): p. 32891-7.;Sibilano, R., B. Frossi and C.E. Pucillo, Mast cell activation: a complex interplay of positive and negative signaling pathways. Eur J Immunol, 2014. 44(9): p. 2558-66.;Key mediators of FceRI;FcεRI signaling-DC;Kelly, B.T. and M.H. Grayson, Immunoglobulin E, what is it good for? Ann Allergy Asthma Immunol, 2016. 116(3): p. 183-7. Acharya, M., et al., CD23/FcepsilonRII: molecular multi-tasking. Clin Exp Immunol, 2010. 162(1): p. 12-23.;Advance in FcεR mediated signaling;Novel molecules and mechanism;Disease-related;Thera

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