6种黄酮类化合物清除超氧阴离子自由基能力的发展关系(中医学范文).docVIP

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6种黄酮类化合物清除超氧阴离子自由基能力的发展关系(中医学范文).doc

6种黄酮类化合物清除超氧阴离子自由基能力的发展关系(中医学范文) 目录 TOC \o 1-9 \h \z \u 目录 1 正文 2 文1:6种黄酮类化合物清除超氧阴离子自由基能力的发展关系 2 1 仪器与试药 4 2 方法与结果 4 2.1 溶液配制 4 2.2 流动注射化学发光法 5 文2:6种黄酮类化合物清除超氧阴离子自由基能力的发展关系 5 1 仪器与试药 7 2 方法与结果 8 2.1 溶液配制 8 2.2 流动注射化学发光法 8 2.3 流动注射化学发光法实验程序编写 9 2.4 O-2·检测体系的优化 9 2.5 抗氧化测定及抑制率计算 9 2.6 6种化合物对O-2·的清除能力 10 3 讨论 10 3.1 黄酮类化合物结构 10 3.2 B环与抗氧化性 11 3.3 C环与抗氧化性 11 3.4 A环与抗氧化性 12 3.5 空间结构与抗氧化性 12 参考文摘引言: 12 原创性声明(模板) 13 文章致谢(模板) 14 正文 6种黄酮类化合物清除超氧阴离子自由基能力的发展关系(中医学范文) 文1:6种黄酮类化合物清除超氧阴离子自由基能力的发展关系 Study of 6 flavonoids compounds for the scavenging superoxide anion free radical ability and the structure-activity relatiohips ZHAO Jing1 LI Yuqin2▲ WANG Fangqiao2 JIA Baoxiu2 LIU Caihong2 WANG Renliang3 1.Taishan Sanatorium of Shandong Province, Shandong Province, Taian 271000, China; 2.School of Pharmacy, Taishan Medical Univeity, Shandong Province, Taian 271016, China; 3.School of Chemical Engineering, Taishan Medical Univeity, Shandong Province, Taian 271016, China [Abstract] Objective To study the scavenging superoxide anion free radical (O-2·) ability of quercetin, myricetin, phloridzin, naringin, puerarin and proanthocyanidi, and to explore their structure-activity relatiohips for removing O-2·. Methods The scavenging O-2· ability was determined by flow injection analysis-pyrogallol-chemiluminescence. IC50 was calculated and used to examine the scavenging free radical ability. Vitamin C was used as positive control. Results The results showed that IC50 of quercetin, myricetin, phloridzin, naringin, puerarin and proanthocyanidi were 0.1547, 0.2048, 0.4623, 0.6157, 1.8098, 2.9798 mu;mol/L, respectively. The scavenging O-2· ability of the 6 compounds were arranged as quercetin, myricetin, phloridzin, naringin, puerarin and proanthocyanidi, and all were higher than Vitamin C (4.9586 mu;mol/L). Conclusion The scavenging O-2· ability of 6 flavonoids compounds have been closely related to their structures: pheno

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