病理学课件-中枢系统肿瘤.pptVIP

Medulloblastoma Seeding of medulloblastoma From : arachnoid cell 蛛网膜细胞 部位 : ~ arachnoid granulation dura 硬脑膜 大体：solid, gritty 砂粒样 光镜：whorl-like pattern psammoma砂粒体 Malignant: rare III. Meningioma 脑膜瘤 meningioma Here is another benign meningioma beneath the dura. These neoplasms are slow growing, but may reach a large size before symptoms lead to detection. Meningioma of sphenoid wing A 181 Schwannoma of a spinal root This schwannoma of a thoracic anterior root was an incidental finding. This tumor is more commonly seen in the posterior roots. * A 165 Cut surface of an acoustic schwannoma The obvious deformity of the rain stem is due to a circumscribed, large extra-axial tumor. The cut surface of the tumor has black areas of hemorrhage, cystic changes, yellow, fatty degeneration and compact, white areas. * A 295 Gemistocytic astrocytoma The tumor cells appear rounded and have well-defined , abundant eosinophilic cytoplasm. * A 295 Gemistocytic astrocytoma The tumor cells appear rounded and have well-defined , abundant eosinophilic cytoplasm. * A 341 Schwannoma Compactly arranged spindle-shaped cells (Antomi type A) and groups of spongy cells (Antomi type B) are intermixed, a characteristic feature of this tumor, which is also known as neurilemmoma and neurinoma. * A 343 Schwannoma This view is of the spongy area shown in 341, at higher magnification. The spongy cells contain lipid granules that dissolve during tissue processing, leaving empty spaces in the cytoplasm. * A 344 palisading Schwannoma This feature is characteristic of this tumor. * * §5 Alzheimer’s disease Degenerative disease 选择性地累及某1~2个功能系统的神经细胞。 老年性痴呆 临床表现：progressive dementia CNS功能的全面衰退，记忆和认知功能逐渐丧失，直至痴呆而死亡。7~10年以上。 Alzheimer’s disease （AD) 1907 Al?is Alzheimer 报告：51岁，女性，多疑，记忆力障碍，时间、地点、定向力障碍，4年半后死亡。 目前 西方：5% 65岁以上， 上海：3% 65岁以上，4.69% 70岁以上 Alzheimer’s disease 病 因 发 病 不明，4个 AD相关基因