(30)--骨巨细胞瘤临床循证诊疗指南.pdfVIP

《中华骨与关节外科杂志》2018 年4 月第11 卷第4 期 Chinese Journal of Bone and Joint Surgery Vol.11, No.4, Apr. 2018 文章编号：2095-9958 （2018 ）04-0276-12 ∙诊疗指南 ∙ DOI：10.3969/j.issn.2095-9958.2018.04.004 骨巨细胞瘤临床循证诊疗指南 【【摘要摘要】】骨巨细胞瘤是常见的交界性骨肿瘤，好发于东亚人群，通过规范的外科手术，很多患者可达到痊愈。对于特殊 部位和难治性骨巨细胞瘤，连续选择性动脉栓塞、Denosumab 和放疗是有效的辅助治疗手段。中国医师协会骨科医师 分会骨肿瘤专业委员会依据循证医学方法制定了《骨巨细胞瘤临床循证诊疗指南》，就诊断流程、不同部位的手术方 式、连续选择性动脉栓塞、Denosumab 和放疗等临床问题进行总结，依据文献证据等级给出相应的推荐等级，旨在为骨 肿瘤医师的临床诊疗提供最佳的、有效的意见参考，从而使患者达到最佳的治疗效果。本指南仅为学术性指导意见， 具体实施时必须依据患者的个体医疗情况而定。 【【关键词关键词】】骨巨细胞瘤；骨肿瘤；指南 Guidelineforclinicalevidence⁃baseddiagnosisandtreatmentofgiantcelltumorofboneGuidelineforclinicalevidence⁃baseddiagnosisandtreatmentofgiantcelltumorofbone Musculoskeletal Tumor Society, Chinese Association of Orthopaedic Surgeons 1* 2* 3* 4* GUO Wei , LI Jianmin , SHEN Jingnan , TU Chongqi (1.Musculoskeletal Tumor Center, Peking University People’s Hospital, Beijing 100044; 2.Department of Orthopaedics, Qilu Hospital of Shandong University, Ji ’nan 250012; 3.Department of Orthopaedics, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080; 4.Department of Orthopaedics, West China Hospital, Sichuan University, Chengdu 610041, China) 【【AbstractAbstract】】Giant cell tumor of bone is a common primary intermediate tumor of the bone especially among East Asians. Standardized surgical treatment can achieve cure of disease for many patients. For refractory cases or tumors of special loca- tions, serial selective arterial embolization, Denosumab and radiotherapy are effective adjuvant treatments. The