8例幼年特發性關節炎病例回顧分析.pdfVIP

50鏡湖醫學2025年6月第25卷第1期MedicalJournalofKiangWu,Jun2025,Vol25.No.1

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8例幼年特發性關節炎病例回顧分析

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陳彥陳燕媚何俊輝

[摘要]目的通過對近年來收治的幼年特發性關節炎(JuvenileidiopathicarthritisJIA)患兒的

病例資料進行回顧性分析，瞭解其特點，為臨床早期診治提供參考依據。方法分析2019~2024

年臨床診斷為幼年特發性關節炎的病例，從年齡、性别、分型、臨床表現、病程等方面進行回

顧性研究。結果8例患兒平均發病年齡為9歲1月，男女發病比例約為1:1，全身型1例、多關

節型1例、少關節型併發虹膜睫狀體炎2例、與附着點炎症相關型4例。全身型以布洛芬加激

素治療為主，其他型以甲氨蝶呤（聯合依那西普或阿達木單抗）治療為主，配合康復治療，8

例患兒均有不同程度的好轉。結論幼年特發性關節炎臨床表現多樣，診斷需排除其他系統疾

病，關節功能障礙、葡萄膜炎導致視力受損是常見併發症，早期診斷、積極治療十分必要。

[關鍵詞]幼年特發性關節炎；回顧性分析；布洛芬

RetrospectiveStudyof8CasesofJuvenileIdiopathicArthritis

CHENYan*,CHANInMei,HOChonFai

DepartmentofPediatrics,KiangWuHospital,Macau

[Abstract]ObjectiveToinvestigatetheclinicalcharacteristicsofjuvenileidiopathicarthritis(JIA)

throughretrospectiveanalysisofpediatriccases,providingreferencesforearlydiagnosisandtreatment.Methods

Clinicaldataofdiagnosedcasebetween2019to2024wereanalyzedretrospectively,focusingonage,gender,

subtypes,clinicalfeatures,anddiseaseprogression.ResultsThemeanageofonsetofthe8patientswas9years

and1month(male-to-femaleratio1:1).SubtypedistributionincludedsystemicJIA(1case),polyarticular

JIA(1case),oligoarticularJIAwithiridocyclitis(2cases),andenthesitis-relatedJIA(4cases).SystemicJIAwas

treatedwithibuprofenandcorticosteroids,whileothersubtypesreceivedmethotrexatecombinedwithetanercept

oradalimumab,supplementedbyrehabilitation.Allcasesshowedclinicalimprovement.ConclusionJIA

exhibitsheterogeneousmanifestationsrequiringdifferentialdiagnosisfromothersystemicdisorders.Common

complicationsincludejointdysfunctionanduveitis-inducedvisualimpairment,highlightingthenecessityof

earlyrecognitiona