谷维素联合罗通定治疗海洛因依赖稽延性戒断症状的效果分析.pdfVIP

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谷维素联合罗通定治疗海洛因依赖稽延性戒断症状的效果分析

白永锋

730000甘肃省第二强制隔离戒毒所医务所，甘肃兰州

doi:10.3969/j.issn.1007-614x.2023.33.005

摘要目的：探讨谷维素联合罗通定治疗海洛因依赖稽延性戒断症状的效果。方法：选取2019年7—12月于甘肃省

第二强制隔离戒毒所接受治疗的80例海洛因依赖稽延性戒断症状患者作为研究对象，采用随机数字表法分为对照组与

观察组，各40例。对照组给予罗通定治疗，观察组在对照组基础上给予谷维素治疗。比较两组临床疗效，失眠、抑

郁、焦虑情况以及症状积分。结果：观察组治疗总有效率高于对照组，差异有统计学意义(P=0.015)。治疗前，两组失

眠严重程度指数量表(ISI)、抑郁自评量表(SDS)、焦虑自评量表(SAS)评分比较，差异无统计学意义(P＞0.05)；治疗后，

两组ISI、SDS、SAS评分低于治疗前，且观察组低于对照组，差异有统计学意义(P＜0.05)。治疗前，两组症状积分比较，

差异无统计学意义(P＞0.05)；治疗后，两组症状积分低于治疗前，且观察组低于对照组，差异有统计学意义(P＜0.05)。

结论：谷维素联合罗通定治疗海洛因依赖稽延性戒断症状的效果显著，可改善患者失眠、焦虑、抑郁等稽延性戒断症

状，降低症状积分。

关键词海洛因依赖稽延性戒断症状；罗通定；谷维素；失眠

AnalysisonEffectofOryzanolCombinedwithRotundineinTreatmentofProtractedWithdrawalSyndromesof

HeroinDependence

BaiYongfeng

MedicalAffairOffice,TheSecondCompulsoryIsolationDrugRehabilitationCenterofGansuProvince,Lanzhou730000,Gansu

Province,China

AbstractObjective:Toexploretheeffectoforyzanolcombinedwithrotundineinthetreatmentofprotractedwithdrawal

syndromesofheroindependence.Methods:Atotalof80patientswithprotractedwithdrawalsyndromesofheroindependencewho

receivedtreatmentintheSecondCompulsoryIsolationDrugRehabilitationCenterofGansuProvincefromJuly2019toDecember

2019wereselectedasthestudysubjects.Theyweredividedintocontrolgroupandobservationgroupaccordingtorandomnumber

tablemethod,with40casesineachgroup.Thecontrolgroupwastreatedwithrotundine,whiletheobservationgroupwastreated

withoryzanolonthebasisofcontrolgroup.Theclinicalefficacy,insomnia,depression,anxietyandsymptomscoreswere

comparedbetweenthetwogroups.Results:Thetotaleffectiverateoftreatmentintheobservationgroupwashigherthanthatinthe

controlgroup,andthedifferencewasstatisticallysignificant(P=0.015).Beforetreatment,ther