F16-Standard-生命科学试剂-MCE.pdfVIP

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F16(Standard)

Cat.No.:HY-100395R

CASNo.:36098-33-6

分⼦式:C₁₆H₁₅IN₂

分⼦量:362.21

作⽤靶点:Apoptosis;ReferenceStandards;Apoptosis

作⽤通路:Apoptosis;Others

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性F16(Standard)是F16(HY-100395)的分析标准品。本产品⽤于研究及分析应⽤。F16是neu过表达细胞的有

效⽣长抑制剂，还可以选择性抑制乳腺上⽪以及多种⼩⿏乳腺肿瘤和⼈乳腺癌细胞系的增殖。F16是线粒体毒

性化合物，根据靶癌细胞的遗传背景触发凋亡或坏死[1][2]。

REFERENCES

[1].FantinVRetal.Anovelmitochondriotoxicsmallmoleculethatselectivelyinhibitstumorcellgrowth.CancerCell.2002Jul;2(1):29-42.

[2].FantinVRetal.F16,amitochondriotoxiccompound,triggersapoptosisornecrosisdependingonthegeneticbackgroundofthetarget

carcinomacell.CancerRes.2004Jan1;64(1):329-36.

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