MELK-8a-hydrochloride-Standard-生命科学试剂-MCE.pdfVIP

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MELK-8ahydrochloride(Standard)

Cat.No.:HY-100368AR

CASNo.:2096992-20-8

分⼦式:C₂₅H₃₃ClN₆O

分⼦量:469.02

作⽤靶点:MELK;ReferenceStandards

作⽤通路:PI3K/Akt/mTOR;Others

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性MELK-8a(hydrochloride)(Standard)是MELK-8a(hydrochloride)(HY-100368A)的分析标准品。本产品⽤于

研究及分析应⽤。MELK-8ahydrochloride是⼀种新颖的母体胚胎亮氨酸拉链激酶（MELK）抑制剂，其IC50值

为2nM。

IC50TargetIC50:2nM(MELK)[1]

REFERENCES

[1].TouréBB,etal.TowardtheValidationofMaternalEmbryonicLeucineZipperKinase:Discovery,OptimizationofHighlyPotentand

SelectiveInhibitors,andPreliminaryBiologyInsight.JMedChem.2016May26;59(10):4711-23.

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Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

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