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Lysyl-phenylalanyl-lysine

Cat.No.:HY-165339

CASNo.:54925-87-0

分⼦式:C₂₁H₃₅N₅O₄

分⼦量:421.53

作⽤靶点:TGF-βReceptor;MMP

作⽤通路:TGF-beta/Smad;MetabolicEnzyme/Protease

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性Lysyl-phenylalanyl-lysine(CompoundKFK)是⼀种三肽，属于与⾎⼩板反应蛋⽩-1(TSP-1)(HY-P0299)相关

的肽段。Lysyl-phenylalanyl-lysine能够激活潜伏型TGF-β1并释放活性TGF-β1，从⽽抑制MMP的异常表

达。Lysyl-phenylalanyl-lysine可⽤于⽪肤衰⽼相关疾病和伤⼝愈合不良的研究[1]。

REFERENCES

[1].CauchardJH,etal.Activationoflatenttransforminggrowthfactorbeta1andinhibitionofmatrixmetalloproteaseactivitybya

thrombospondin-liketripeptidelinkedtoelaidicacid.BiochemPharmacol.2004Jun1;67(11):2013-22.

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